C12Y 304/22
Cysteine endopeptidases
Official title: Cysteine endopeptidases (3.4.22)
C12Y304/22 (Cysteine endopeptidases) appears on 388 US grants and 808 published applications in this corpus.
Search patents in C12Y- Granted patents
- 388
- Published applications
- 808
- Assignees
- 442
- Inventors
- 1,545
- Latest grant
- 6 Oct 2026
Filings by year
| Year | Granted patents | Published applications |
|---|---|---|
| 1982 | 1 | 0 |
| 1983 | 0 | 0 |
| 1984 | 0 | 0 |
| 1985 | 0 | 0 |
| 1986 | 0 | 0 |
| 1987 | 2 | 0 |
| 1988 | 0 | 0 |
| 1989 | 2 | 0 |
| 1990 | 0 | 0 |
| 1991 | 1 | 0 |
| 1992 | 1 | 0 |
| 1993 | 0 | 0 |
| 1994 | 2 | 0 |
| 1995 | 0 | 0 |
| 1996 | 5 | 0 |
| 1997 | 1 | 0 |
| 1998 | 2 | 0 |
| 1999 | 4 | 0 |
| 2000 | 2 | 0 |
| 2001 | 4 | 0 |
| 2002 | 2 | 6 |
| 2003 | 5 | 11 |
| 2004 | 3 | 13 |
| 2005 | 3 | 6 |
| 2006 | 4 | 7 |
| 2007 | 5 | 11 |
| 2008 | 2 | 8 |
| 2009 | 2 | 10 |
| 2010 | 2 | 10 |
| 2011 | 5 | 21 |
| 2012 | 5 | 13 |
| 2013 | 7 | 16 |
| 2014 | 9 | 25 |
| 2015 | 14 | 52 |
| 2016 | 25 | 37 |
| 2017 | 19 | 49 |
| 2018 | 24 | 49 |
| 2019 | 38 | 67 |
| 2020 | 30 | 37 |
| 2021 | 31 | 49 |
| 2022 | 30 | 55 |
| 2023 | 28 | 64 |
| 2024 | 18 | 83 |
| 2025 | 34 | 57 |
| 2026 | 16 | 52 |
By publication year. Applications have been published since 2001. 2026 runs to 8 Oct.
Subgroups
Granted patents
- C12Y 304/22002Papain79
- C12Y 304/2207Sortase a52
- C12Y 304/22062Caspase-944
- C12Y 304/22033Fruit bromelain , i.e. juice bromelain35
- C12Y 304/22032Stem bromelain34
- C12Y 304/22044Nuclear-inclusion-a endopeptidase25
- C12Y 304/22004Bromelain21
- C12Y 304/22036Caspase-1 , i.e. interleukin-1-beta-convertase14
All 60 subgroupsShow fewer
- C12Y 304/22055Caspase-214
- C12Y 304/22056Caspase-313
- C12Y 304/22003Ficain11
- C12Y 304/22001Cathepsin b10
- C12Y 304/22061Caspase-88
- C12Y 304/22015Cathepsin l7
- C12Y 304/2201Streptopain6
- C12Y 304/22028Picornain 3c6
- C12Y 304/22031Ananain5
- C12Y 304/22008Clostripain4
- C12Y 304/22025Glycyl endopeptidase4
- C12Y 304/22038Cathepsin k4
- C12Y 304/22041Cathepsin f4
- C12Y 304/2206Caspase-74
- C12Y 304/22006Chymopapain3
- C12Y 304/22017Calpain3
- C12Y 304/22059Caspase-63
- C12Y 304/22063Caspase-103
- C12Y 304/22071Sortase b3
- C12Y 304/22007Asclepain2
- C12Y 304/22014Actinidain2
- C12Y 304/22027Cathepsin s2
- C12Y 304/22053Calpain-2 , i.e. m-calpain2
- C12Y 304/22054Calpain-3 , i.e. calpain p942
- C12Y 304/22057Caspase-42
- C12Y 304/22064Caspase-112
- C12Y 304/22065Peptidase 12
- C12Y 304/22034Legumain , i.e. asparaginyl endopeptidase1
- C12Y 304/22035Histolysain1
- C12Y 304/22049Separase1
- C12Y 304/2205V-cath endopeptidase1
- C12Y 304/22052Calpain-11
- C12Y 304/22058Caspase-51
- C12Y 304/22067Zingipain1
- C12Y 304/22069Sars coronavirus main proteinase1
- C12Y 304/22016Cathepsin h0
- C12Y 304/22024Cathepsin t0
- C12Y 304/22026Cancer procoagulant0
- C12Y 304/22029Picornain 2a0
- C12Y 304/2203Caricain0
- C12Y 304/22037Gingipain r0
- C12Y 304/22039Adenain0
- C12Y 304/2204Bleomycin hydrolase0
- C12Y 304/22042Cathepsin o0
- C12Y 304/22043Cathepsin v0
- C12Y 304/22045Helper-component proteinase0
- C12Y 304/22046L-peptidase0
- C12Y 304/22047Gingipain k0
- C12Y 304/22048Staphopain0
- C12Y 304/22051Cruzipain0
- C12Y 304/22066Calicivirin0
- C12Y 304/22068Ulp1 peptidase0
Recent patents
- Engineered cells and uses thereof6 Oct 2026US 12,751,929 B2Ohio State Innovation Foundation
- Protease composition6 Oct 2026US 12,751,997 B2Anatara Lifesciences Limited
- CAS12B enzymes and systems6 Oct 2026US 12,753,406 B2Massachusetts Institute of Technology
- Bromelain protease, bromelain, jacalin-like lectin, extract from the stem and/or the fruit of a pineapple plant, combination preparation, bromelain protease inhibitor, protein/protease mix, and glycated bromelain protein formed by exogenous non-enzymatic glycation, for use in the treatment or prophylaxis of virus infections caused by coronaviruses in a human or animal15 Sep 2026US 12,734,223 B2Helmholtz-Institut FüR Pharmazeutische Forschung Saarland
- RNA-guided nuclease15 Sep 2026US 12,735,691 B1Inari Agriculture Technology, Inc.
- Non-human animal, kit, and method for producing replacement organ24 Sep 2026US 2026/0283124 A1The Jikei University
- Regulated cells expressing cytokines24 Sep 2026US 2026/0286288 A1
- Site-specific orthogonal bioconjugate modality and application thereof24 Sep 2026US 2026/0286332 A1Genequantum Healthcare (Suzhou) Co., Ltd.
- Methods for developing companion supplements for dogs, related compositions, and systems17 Sep 2026US 2026/0272876 A1Life's Abundance
- Intracellular Delivery of Therapeutic Cargos and Viral RNAS by Engineered Salmonella17 Sep 2026US 2026/0272995 A1The Trustees of Columbia University in the City of New York
Most cited
By later US patents
- Antisense modulation of caspase 3 expression153US 6,303,374 B1Isis Pharmaceuticals, Inc. · 2001
- Methods for correcting presenilin point mutations123US 9,068,179 B1President and Fellows of Harvard College · 2015
- Methods for nucleic acid editing121US 9,840,699 B2President and Fellows of Harvard College · 2017
- Evolution of bond-forming enzymes82US 9,267,127 B2President and Fellows of Harvard College · 2016
- Reduced-pressure treatment systems and methods employing debridement mechanisms75US 8,486,032 B2KCI Licensing, Inc. · 2013