Site-specific orthogonal bioconjugate modality and application thereof

Abstract

Provided is the process of producing an immunoligand/payload conjugate, in particularly, relates to a novel enzyme site-specific conjugation technology with dual enzyme orthogonal catalysis, comprising: conjugating a first payload to an immunoligand through the enzymatic catalysis of a first enzyme, conjugating a second payload to the immunoligand through enzymatic catalysis of a second enzyme, wherein the first enzyme is different from the second enzyme.

Dependencies are inferred from the claim text.