Back to results
US 2026/0283124 A1Published application
Non-human animal, kit, and method for producing replacement organ
AssigneeThe Jikei University
InventorsShuichiro YAMANAKA, Takashi YOKOO, Kenji MATSUI
Life of this patent
Estimating the term…
Abstract
A non-human animal including a system configured to kill a target cell in vivo, in which the target cell includes a chromosome having a cell-specific promoter and an exogenous caspase 9 gene in which expression is inducible downstream of the cell-specific promoter, or a chromosome having a high-expression promoter and an exogenous caspase 9 gene in which expression is inducible downstream of the high-expression promoter.
Claims7
A non-human animal comprising:
- a system configured to kill a target cell in vivo,
- wherein the target cell includes a chromosome having a cell-specific promoter and an exogenous caspase 9 gene in which expression is inducible downstream of the cell-specific promoter, or a chromosome having a high-expression promoter and an exogenous caspase 9 gene in which expression is inducible downstream of the high-expression promoter.
Dependencies are inferred from the claim text.