C12N 15/67
General methods for enhancing the expression
C12N15/67 (General methods for enhancing the expression) appears on 1,624 US grants and 2,102 published applications in this corpus.
Search patents in C12N- Granted patents
- 1,624
- Published applications
- 2,102
- Assignees
- 1,062
- Inventors
- 4,378
- Latest grant
- 29 Sep 2026
Filings by year
| Year | Granted patents | Published applications |
|---|---|---|
| 1982 | 1 | 0 |
| 1983 | 1 | 0 |
| 1984 | 2 | 0 |
| 1985 | 4 | 0 |
| 1986 | 2 | 0 |
| 1987 | 15 | 0 |
| 1988 | 17 | 0 |
| 1989 | 16 | 0 |
| 1990 | 22 | 0 |
| 1991 | 20 | 0 |
| 1992 | 28 | 0 |
| 1993 | 25 | 0 |
| 1994 | 8 | 0 |
| 1995 | 16 | 0 |
| 1996 | 35 | 0 |
| 1997 | 43 | 0 |
| 1998 | 72 | 0 |
| 1999 | 63 | 0 |
| 2000 | 51 | 0 |
| 2001 | 45 | 7 |
| 2002 | 27 | 47 |
| 2003 | 42 | 68 |
| 2004 | 25 | 65 |
| 2005 | 29 | 57 |
| 2006 | 27 | 55 |
| 2007 | 29 | 44 |
| 2008 | 27 | 60 |
| 2009 | 26 | 61 |
| 2010 | 31 | 52 |
| 2011 | 40 | 75 |
| 2012 | 31 | 57 |
| 2013 | 44 | 86 |
| 2014 | 45 | 77 |
| 2015 | 47 | 85 |
| 2016 | 61 | 92 |
| 2017 | 47 | 86 |
| 2018 | 58 | 96 |
| 2019 | 54 | 108 |
| 2020 | 79 | 111 |
| 2021 | 57 | 115 |
| 2022 | 61 | 120 |
| 2023 | 64 | 132 |
| 2024 | 68 | 114 |
| 2025 | 72 | 133 |
| 2026 | 47 | 99 |
By publication year. Applications have been published since 2001. 2026 runs to 8 Oct.
Subgroups
Granted patents
Recent patents
- Riboswitch modulated gene therapy for retinal diseases29 Sep 2026US 12,747,441 B2The Medical College of Wisconsin, Inc.
- Integration of nucleic acid constructs into eukaryotic cells with a transposase from oryzias22 Sep 2026US 12,742,171 B2Dna Twopointo Inc.
- Engineered DNA molecule for coding RNA22 Sep 2026US 12,742,172 B2Rinuagene Biotechnology Co., Ltd.
- Proteins containing multiple, different unnatural amino acids and methods of making and using such proteins14 Jul 2026US 12,680,122 B2The Trustees of Boston College
- Aptamer and ribozyme equilibrium shifting (ARES) RNA circuits and uses thereof7 Jul 2026US 12,674,171 B2Trustees of Boston University
- Nucleic acids encoding crispr-associated proteins and uses thereof8 Oct 2026US 2026/0308602 A1CureVac AG
- Promoter for gene expression in retinal cells, and vector system comprising same1 Oct 2026US 2026/0295081 A1Korea Research Institute of Bioscience and Biotechnology
- 3'-utr sequences for stabilization of rna1 Oct 2026US 2026/0297594 A1BioNTech SE
- Polynucleotide molecule comprising poly(a) and use thereof24 Sep 2026US 2026/0286369 A1Shenzhen Shenxin Biotechnology Co., Ltd.
- Nonsense mediated decay inhibitor compounds17 Sep 2026US 2026/0272923 A1The Johns Hopkins University
Most cited
By later US patents
- Regulation of endogenous gene expression in cells using zinc finger proteins648US 6,534,261 B1Sangamo BioSciences, Inc. · 2003
- Method of identifying a stochastically-generated peptide, polypeptide, or protein having ligand binding property and compositions thereof519US 5,723,323 A1998
- Methods of modifying eukaryotic cells420US 6,596,541 B2Regeneron Pharmaceuticals, Inc. · 2003
- Regulation of endogenous gene expression in cells using zinc finger proteins395US 6,824,978 B1Sangamo BioSciences, Inc. · 2004
- Modulation of endogenous gene expression in cells383US 6,933,113 B2Sangamo BioSciences, Inc. · 2005