Mutation or genetic engineering
Official title: Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor (mutants or genetically engineered microorganisms, per se C12N1/00, C12N5/00, C12N7/00; new plants per se A01H; plant reproduction by tissue culture techniques A01H4/00; new animals per se A01K67/00; use of medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases, gene therapy A61K48/00)
C12N15/00 (Mutation or genetic engineering) appears on 66,864 US grants and 106,906 published applications in this corpus.
Search patents in C12N- Granted patents
- 66,864
- Published applications
- 106,906
- Assignees
- 18,690
- Inventors
- 138,081
- Latest grant
- 6 Oct 2026
Filings by year
| Year | Granted patents | Published applications |
|---|---|---|
| 1976 | 7 | 0 |
| 1977 | 1 | 0 |
| 1978 | 1 | 0 |
| 1979 | 4 | 0 |
| 1980 | 6 | 0 |
| 1981 | 14 | 0 |
| 1982 | 45 | 0 |
| 1983 | 40 | 0 |
| 1984 | 58 | 0 |
| 1985 | 60 | 0 |
| 1986 | 66 | 0 |
| 1987 | 110 | 0 |
| 1988 | 131 | 0 |
| 1989 | 171 | 0 |
| 1990 | 190 | 0 |
| 1991 | 220 | 0 |
| 1992 | 314 | 0 |
| 1993 | 364 | 0 |
| 1994 | 362 | 0 |
| 1995 | 393 | 0 |
| 1996 | 694 | 0 |
| 1997 | 1140 | 0 |
| 1998 | 1537 | 0 |
| 1999 | 1570 | 0 |
| 2000 | 1432 | 0 |
| 2001 | 1565 | 352 |
| 2002 | 1410 | 2110 |
| 2003 | 1307 | 4111 |
| 2004 | 1103 | 3001 |
| 2005 | 902 | 2927 |
| 2006 | 1299 | 2757 |
| 2007 | 1356 | 2329 |
| 2008 | 1138 | 2504 |
| 2009 | 1265 | 3177 |
| 2010 | 1694 | 3207 |
| 2011 | 1708 | 3372 |
| 2012 | 1836 | 3095 |
| 2013 | 1882 | 3455 |
| 2014 | 2255 | 3922 |
| 2015 | 2686 | 4119 |
| 2016 | 2762 | 4195 |
| 2017 | 2964 | 4285 |
| 2018 | 3014 | 4717 |
| 2019 | 3245 | 5667 |
| 2020 | 3453 | 5734 |
| 2021 | 3435 | 6028 |
| 2022 | 3361 | 6565 |
| 2023 | 3116 | 6747 |
| 2024 | 3131 | 7050 |
| 2025 | 3460 | 6537 |
| 2026 | 2587 | 4943 |
By publication year. Applications have been published since 2001. 2026 runs to 8 Oct.
Subgroups
Recent patents
- Preventing and treating amyloid-beta deposition by stimulation of innate immunity6 Oct 2026US 12,751,964 B2New York University
- Method for optimized RIG-I ligands6 Oct 2026US 12,751,965 B2
- Composition for use in treating dystrophic epidermolysis bullosa6 Oct 2026US 12,751,974 B2Osaka University
- Methods and compositions of chondrisomes6 Oct 2026US 12,751,977 B2Children's Medical Center Corporation
- Tumor-targeting Salmonella gallinarum strain and use thereof6 Oct 2026US 12,751,978 B2Industry Foundation of Chonnam National University
- Transgenic model of human cardiomyopathy8 Oct 2026US 2026/0305586 A1Stichting Genetische Hartspierziekte PLN
- Humanized ace2-expressing transgenic mouse susceptible to sars-cov-2 virus infection and method for producing same8 Oct 2026US 2026/0305587 A1Seoul National University R&Db Foundation
- Methods and compositions for microbial delivery of double stranded rna8 Oct 2026US 2026/0305618 A1Rnaissance AG LLC
- Composition and Method for Topical Trans-spinal Delivery of Nucleic Acids and Small Molecules8 Oct 2026US 2026/0306414 A13P Biotechnologies, Inc.
- Active loading of biomolecular cargo into engineered vesicles8 Oct 2026US 2026/0306415 A1Northwestern University
Most cited
- Process for amplifying nucleic acid sequences5,960US 4,683,202 ACetus Corporation · 1987
- Mutant dwarfism gene of petunia5,133US 5,523,520 AGoldsmith Seeds, Inc. · 1996
- Recombinant immunoglobin preparations4,785US 4,816,567 AGenentech, Inc. · 1989
- Directed evolution of novel binding proteins2,450US 5,223,409 AProtein Engineering Corporation · 1993
- Soybean transformation and regeneration methods2,169US 5,968,830 AMississippi State University · 1999