Tumor-targeting Salmonella gallinarum strain and use thereof
AssigneeIndustry Foundation of Chonnam National University
InventorsHyon El Choy, Jae Ho Jeong, Dae Jin Lim, Hyung Ju Lim, Kwangsoo Kim
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Abstract
The present invention relates to a tumor-targeting Salmonella gallinarum strain and the use thereof. The tumor-targeting Salmonella gallinarum strain has excellent tumor proliferation inhibitory activity and enables tumor-specific targeting, and thus can be utilized for treatment and imaging of tumors without any side effects.
Claims4
A method for treatment of a tumor in a subject, the method comprising administering to the subject a composition comprising an attenuated Salmonella gallinarum strain lacking guanosine tetraphosphate (ppGpp) production capability, wherein the strain lacks a glmS gene.
Dependencies are inferred from the claim text.