C12N 15/02
Preparation of hybrid cells by fusion of two or more cells
Official title: Preparation of hybrid cells by fusion of two or more cells, e.g. protoplast fusion {(monoclonal antibodies C07K16/00; apparatus for cell fusion C12M)}
C12N15/02 (Preparation of hybrid cells by fusion of two or more cells) appears on 163 US grants and 170 published applications in this corpus.
Search patents in C12N- Granted patents
- 163
- Published applications
- 170
- Assignees
- 153
- Inventors
- 485
- Latest grant
- 1 Sep 2026
Filings by year
| Year | Granted patents | Published applications |
|---|---|---|
| 1979 | 3 | 0 |
| 1980 | 0 | 0 |
| 1981 | 1 | 0 |
| 1982 | 0 | 0 |
| 1983 | 2 | 0 |
| 1984 | 1 | 0 |
| 1985 | 0 | 0 |
| 1986 | 1 | 0 |
| 1987 | 2 | 0 |
| 1988 | 3 | 0 |
| 1989 | 3 | 0 |
| 1990 | 3 | 0 |
| 1991 | 0 | 0 |
| 1992 | 3 | 0 |
| 1993 | 6 | 0 |
| 1994 | 5 | 0 |
| 1995 | 1 | 0 |
| 1996 | 3 | 0 |
| 1997 | 4 | 0 |
| 1998 | 3 | 0 |
| 1999 | 3 | 0 |
| 2000 | 1 | 0 |
| 2001 | 2 | 0 |
| 2002 | 2 | 3 |
| 2003 | 0 | 0 |
| 2004 | 0 | 5 |
| 2005 | 2 | 0 |
| 2006 | 2 | 2 |
| 2007 | 1 | 0 |
| 2008 | 1 | 0 |
| 2009 | 0 | 1 |
| 2010 | 0 | 2 |
| 2011 | 0 | 2 |
| 2012 | 1 | 2 |
| 2013 | 3 | 7 |
| 2014 | 3 | 7 |
| 2015 | 9 | 13 |
| 2016 | 8 | 10 |
| 2017 | 10 | 20 |
| 2018 | 9 | 26 |
| 2019 | 8 | 14 |
| 2020 | 15 | 15 |
| 2021 | 13 | 8 |
| 2022 | 6 | 12 |
| 2023 | 5 | 8 |
| 2024 | 6 | 6 |
| 2025 | 6 | 3 |
| 2026 | 3 | 4 |
By publication year. Applications have been published since 2001. 2026 runs to 8 Oct.
Subgroups
Granted patents
Recent patents
- Cell lines for high level production of protein selected for rapid proliferation1 Sep 2026US 12,723,244 B2CHO Plus, Inc.
- Alignment and fusion of cells with an electrical field19 May 2026US 12,630,816 B2Hewlett-Packard Development Company, L. P.
- Transgenic animal for producing diversified antibodies that have the same light chain II10 Feb 2026US 12,543,710 B2Crystal Bioscience Inc.
- Chloramphenicol resistant split protein and uses thereof30 Sep 2025US 12,428,637 B2Technology Innovation Momentum Fund (Israel) Limited Partnership
- Transgenic animal for producing diversified antibodies that have the same light chain I9 Sep 2025US 12,408,640 B2Crystal Bioscience Inc.
- Alignment and fusion of cells with an electrical field10 Sep 2026US 2026/0265725 A1Hewlett-Packard Development Company, L. P.
- Chimeric genome organisms and methods synthesizing thereof4 Jun 2026US 2026/0152735 A1California Institute of Technology
- Genetically modified strain of aureobasidium pullulans and use thereof for producing bioproduct in high yield7 May 2026US 2026/0125718 A1Safion Renewables Inc.
- Transgenic animal for producing diversified antibodies that have the same light chain i19 Mar 2026US 2026/0076347 A1Crystal Bioscience Inc.
- Chloramphenicol resistant split protein and uses thereof30 Oct 2025US 2025/0333724 A1Technology Innovation Momentum Fund (Israel) Limited Partnership
Most cited
By later US patents
- Method for making recombinant yeast artificial chromosomes by minimizing diploid doubling during mating157US 5,643,763 AGenPharm International, Inc. · 1997
- Apparatus and methods for electroporation and electrofusion144US 5,173,158 A1992
- Apparatus and methods for electroporation and electrofusion123US 5,283,194 A1994
- Use of distributed temperature sensors during wellbore treatments120US 7,055,604 B2Schlumberger Technology Corporation · 2006
- Method for inserting foreign genes into cells using pulsed radiofrequency116US 4,970,154 ABaylor College of Medicine · 1990