Genetically modified strain of aureobasidium pullulans and use thereof for producing bioproduct in high yield
AssigneeSafion Renewables Inc.
InventorsLauren Ann Riley Drumm, Andrew John Borchert, Julia Rae Friedman
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Abstract
Provided are genetically modified strains of Aureobasidium pullulans that can produce a bioproduct with increased productivity and a method of producing a bioproduct using the same, wherein the genetically modified strain of Aureobasidium pullulans comprises an overexpression of a functional VHb protein and an overexpression of a functional PacC protein and is grown under conditions required to support the production of the bioproduct to collect the bioproduct in a high yield.
Claims20
A method of producing a bioproduct comprising:
- growing a genetically modified strain of Aureobasidium pullulans under conditions required to support the production of the bioproduct,
- wherein the genetically modified strain of Aureobasidium pullulans comprises an overexpression of a functional VHb protein having at least 90% sequence homology with the sequence set forth in SEQ ID NO. 1, and an overexpression of a functional PacC protein;
- and
- collecting the bioproduct from the genetically modified strain of Aureobasidium pullulans.
A composition comprising a strain of Aureobasidium pullulans, wherein the strain comprises:
- an overabundance of a functional VHb protein having at least 90% sequence homology with the sequence set forth in SEQ ID NO:
- 1;
- and
- an overabundance of a functional PacC protein.
Dependencies are inferred from the claim text.