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AssigneeKorea Research Institute of Bioscience and Biotechnology
InventorsKyung-Sook CHUNG, Hyeon Ki JANG, Jae-Eun KWON, Seung-Hyun KIM, Ok Seon KWON, Jiwon AHN, Myung Jin SON
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The present invention relates to a promoter for gene expression in retinal cells, and a vector system comprising same. The promoter for gene expression in retinal cells and the vector system including same according to the present invention have a minimal unit for promoter activity and, unlike existing known promoters in retinal cells, maintain a high level of expression of a target gene, and thus can be used to maximize the expression of the target protein in retinal cells.
-20. (canceled)
An expression cassette comprising:
A vector comprising an expression cassette comprising (a) a promoter of 100 to 400 nucleotides in length comprising as a core nucleotide sequence a nucleotide sequence having at least 90% identity to the sequence of SEQ ID NO:
A method for enhancing expression of a target gene in the retina, comprising administering an expression cassette comprising (a) a promoter of 100 to 400 nucleotides in length comprising as a core nucleotide sequence a nucleotide sequence having at least 90% identity to the sequence of SEQ ID NO:
Dependencies are inferred from the claim text.