A61K 31/454
Containing a five-membered ring with nitrogen as a ring hetero atom
Official title: containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
A61K31/454 (Containing a five-membered ring with nitrogen as a ring hetero atom) appears on 2,989 US grants and 5,561 published applications in this corpus.
Search patents in A61K- Granted patents
- 2,989
- Published applications
- 5,561
- Assignees
- 1,863
- Inventors
- 12,157
- Latest grant
- 29 Sep 2026
Filings by year
| Year | Granted patents | Published applications |
|---|---|---|
| 1977 | 1 | 0 |
| 1978 | 0 | 0 |
| 1979 | 0 | 0 |
| 1980 | 0 | 0 |
| 1981 | 0 | 0 |
| 1982 | 0 | 0 |
| 1983 | 0 | 0 |
| 1984 | 0 | 0 |
| 1985 | 0 | 0 |
| 1986 | 0 | 0 |
| 1987 | 0 | 0 |
| 1988 | 0 | 0 |
| 1989 | 0 | 0 |
| 1990 | 0 | 0 |
| 1991 | 0 | 0 |
| 1992 | 1 | 0 |
| 1993 | 4 | 0 |
| 1994 | 2 | 0 |
| 1995 | 3 | 0 |
| 1996 | 10 | 0 |
| 1997 | 22 | 0 |
| 1998 | 44 | 0 |
| 1999 | 31 | 0 |
| 2000 | 38 | 0 |
| 2001 | 38 | 25 |
| 2002 | 48 | 75 |
| 2003 | 44 | 85 |
| 2004 | 25 | 102 |
| 2005 | 34 | 120 |
| 2006 | 35 | 95 |
| 2007 | 27 | 103 |
| 2008 | 45 | 107 |
| 2009 | 43 | 127 |
| 2010 | 55 | 130 |
| 2011 | 60 | 120 |
| 2012 | 80 | 124 |
| 2013 | 110 | 218 |
| 2014 | 149 | 266 |
| 2015 | 190 | 298 |
| 2016 | 179 | 297 |
| 2017 | 223 | 304 |
| 2018 | 228 | 301 |
| 2019 | 192 | 298 |
| 2020 | 193 | 313 |
| 2021 | 184 | 307 |
| 2022 | 159 | 333 |
| 2023 | 121 | 327 |
| 2024 | 128 | 341 |
| 2025 | 136 | 391 |
| 2026 | 107 | 354 |
By publication year. Applications have been published since 2001. 2026 runs to 8 Oct.
Recent patents
- Combination therapies of FASN inhibitors with thyroid hormone receptor agonists29 Sep 2026US 12,746,242 B2Sagimet Biosciences Inc.
- Imidazole-based synthetic lipidoids for in vivo mRNA delivery into immune cells29 Sep 2026US 12,747,214 B2Trustees of Tufts College
- Compounds for treatment of excitotoxicity29 Sep 2026US 12,747,238 B2Nyrada Pty Ltd
- Orally-disintegrating film comprising naratriptan22 Sep 2026US 12,740,974 B2CMG Pharmaceutical Co., Ltd.
- Piperidine urea derivatives for cancer therapy15 Sep 2026US 12,734,164 B2NeuroPn Therapeutics, Inc.
- Composition for removing and inhibiting senescent cells, and uses thereof8 Oct 2026US 2026/0306460 A1Lifeceutix Co., Ltd.
- Tomm6-interacting extracts and compounds for use in the treatment and prophylaxis of nervous system diseases, atherosclerosis, hepatitis b infection and human papilloma virus (hpv) infection8 Oct 2026US 2026/0306473 A1
- Methods of treating diseases and disorders associated with foxp3 expression8 Oct 2026US 2026/0306482 A1Northwestern University
- Inverse agonists of rar related orphan receptors (rors)8 Oct 2026US 2026/0306484 A111949098 CANADA INC. (NUREDCO) c/o Jean I. TCHERVENKOV
- 5-ht2a receptor inverse agonist, and preparation method therefor and use thereof8 Oct 2026US 2026/0308142 A1Luye Innomind Pharma Shijiazhuang Co., Ltd.
Most cited
By later US patents
- Methods for treating multiple myeloma with 3-(4-amino-1-oxo-1,3-dihydro-isoindol-2-yl)-piperidine-2,6-dione after stem cell transplantation733US 9,101,621 B2Celgene Corporation · 2015
- Methods and compositions for inhibition of angiogenesis231US 5,712,291 AChildren's Medical Center Corporation · 1998
- Methods and compositions for inhibition of angiogenesis185US 5,629,327 AChildren's Hospital Medical Center · 1997
- Pharmaceutical composition containing acid addition salt of basic drug163US 6,255,502 B1Farmarc Nederland BV · 2001
- Methods and compositions for inhibition of angiogenesis152US 5,593,990 AChildren's Medical Center Corporation · 1997