A61K 31/4453
Only substituted in position 1
Official title: only substituted in position 1, e.g. propipocaine, diperodon
A61K31/4453 (Only substituted in position 1) appears on 460 US grants and 673 published applications in this corpus.
Search patents in A61K- Granted patents
- 460
- Published applications
- 673
- Assignees
- 439
- Inventors
- 1,648
- Latest grant
- 6 Oct 2026
Filings by year
| Year | Granted patents | Published applications |
|---|---|---|
| 1976 | 1 | 0 |
| 1977 | 0 | 0 |
| 1978 | 1 | 0 |
| 1979 | 0 | 0 |
| 1980 | 0 | 0 |
| 1981 | 0 | 0 |
| 1982 | 0 | 0 |
| 1983 | 0 | 0 |
| 1984 | 0 | 0 |
| 1985 | 0 | 0 |
| 1986 | 0 | 0 |
| 1987 | 0 | 0 |
| 1988 | 0 | 0 |
| 1989 | 0 | 0 |
| 1990 | 0 | 0 |
| 1991 | 0 | 0 |
| 1992 | 1 | 0 |
| 1993 | 1 | 0 |
| 1994 | 2 | 0 |
| 1995 | 4 | 0 |
| 1996 | 7 | 0 |
| 1997 | 17 | 0 |
| 1998 | 10 | 0 |
| 1999 | 9 | 0 |
| 2000 | 11 | 0 |
| 2001 | 12 | 9 |
| 2002 | 13 | 16 |
| 2003 | 9 | 17 |
| 2004 | 8 | 24 |
| 2005 | 6 | 16 |
| 2006 | 10 | 15 |
| 2007 | 3 | 12 |
| 2008 | 4 | 19 |
| 2009 | 9 | 20 |
| 2010 | 11 | 29 |
| 2011 | 7 | 15 |
| 2012 | 19 | 23 |
| 2013 | 14 | 21 |
| 2014 | 21 | 42 |
| 2015 | 25 | 45 |
| 2016 | 30 | 36 |
| 2017 | 34 | 43 |
| 2018 | 18 | 35 |
| 2019 | 26 | 27 |
| 2020 | 22 | 36 |
| 2021 | 18 | 33 |
| 2022 | 15 | 34 |
| 2023 | 16 | 30 |
| 2024 | 18 | 23 |
| 2025 | 12 | 29 |
| 2026 | 16 | 24 |
By publication year. Applications have been published since 2001. 2026 runs to 8 Oct.
Recent patents
- Small molecule inhibitors of viral replication6 Oct 2026US 12,751,963 B2The Trustees of Princeton University
- Pharmaceutical composition of pitolisant hydrochloride and their process for the preparation22 Sep 2026US 12,740,972 B2Msn Laboratories Private Limited, R&D Center
- SerpinB3 inhibitor piperidinpropionic acid for tumor treatment15 Sep 2026US 12,734,162 B2Universita' Degli Studi Di Padova
- Compositions and methods for treating idiopathic pulmonary fibrosis8 Sep 2026US 12,728,121 B2Seyltx, Inc.
- Arylsulfonamides as orexin receptor agonists8 Sep 2026US 12,729,178 B2Research Triangle Institute
- Inhibitors of nsun1- and nsun2-mediated active structures8 Oct 2026US 2026/0306459 A1
- Flavored topical anesthetic10 Sep 2026US 2026/0263409 A1
- Compositions and methods for diagnosing and treating dystonia10 Sep 2026US 2026/0266848 A1Duke University
- Natural medicinal composition20 Aug 2026US 2026/0240934 A1
- Inhibitors of the ras oncoprotein, methods of making and methods of use thereof13 Aug 2026US 2026/0232689 A1University of Louisville Research Foundation, Inc.
Most cited
By later US patents
- Compositions and methods for topical administration of pharmaceutically active agents369US 5,719,197 ANoven Pharmaceuticals, Inc. · 1998
- Compositions and methods for topical administration of pharmaceutically active agents324US 5,446,070 ANover Pharmaceuticals, Inc. · 1995
- Compositions and methods for topical administration of pharmaceutically active agents216US 5,234,957 ANoven Pharmaceuticals, Inc. · 1993
- Compositions and methods for topical administration of pharmaceutically active agents166US 5,332,576 ANoven Pharmaceuticals, Inc. · 1994
- Delivery system for the localized administration of medicaments to the upper respiratory tract and methods for preparing and using same152US 5,912,007 AWarner-Lambert Company · 1999