C12Y 304/24
Metalloendopeptidases
Official title: Metalloendopeptidases (3.4.24)
C12Y304/24 (Metalloendopeptidases) appears on 1,032 US grants and 1,807 published applications in this corpus.
Search patents in C12Y- Granted patents
- 1,032
- Published applications
- 1,807
- Assignees
- 623
- Inventors
- 2,398
- Latest grant
- 29 Sep 2026
Filings by year
| Year | Granted patents | Published applications |
|---|---|---|
| 1984 | 1 | 0 |
| 1985 | 0 | 0 |
| 1986 | 0 | 0 |
| 1987 | 1 | 0 |
| 1988 | 0 | 0 |
| 1989 | 1 | 0 |
| 1990 | 1 | 0 |
| 1991 | 1 | 0 |
| 1992 | 0 | 0 |
| 1993 | 1 | 0 |
| 1994 | 0 | 0 |
| 1995 | 4 | 0 |
| 1996 | 2 | 0 |
| 1997 | 7 | 0 |
| 1998 | 11 | 0 |
| 1999 | 8 | 0 |
| 2000 | 9 | 0 |
| 2001 | 5 | 2 |
| 2002 | 5 | 12 |
| 2003 | 5 | 15 |
| 2004 | 4 | 7 |
| 2005 | 6 | 23 |
| 2006 | 7 | 29 |
| 2007 | 7 | 22 |
| 2008 | 11 | 29 |
| 2009 | 6 | 33 |
| 2010 | 15 | 42 |
| 2011 | 19 | 50 |
| 2012 | 27 | 61 |
| 2013 | 29 | 47 |
| 2014 | 45 | 67 |
| 2015 | 58 | 110 |
| 2016 | 60 | 133 |
| 2017 | 65 | 133 |
| 2018 | 92 | 113 |
| 2019 | 84 | 121 |
| 2020 | 81 | 111 |
| 2021 | 73 | 119 |
| 2022 | 67 | 101 |
| 2023 | 54 | 120 |
| 2024 | 63 | 119 |
| 2025 | 51 | 105 |
| 2026 | 46 | 83 |
By publication year. Applications have been published since 2001. 2026 runs to 8 Oct.
Subgroups
Granted patents
- C12Y 304/24069Bontoxilysin , i.e. botulinum neurotoxin403
- C12Y 304/24007Interstitial collagenase , i.e. matrix metalloprotease 1 or mmp182
- C12Y 304/24003Microbial collagenase63
- C12Y 304/24087Adamts13 endopeptidase48
- C12Y 304/24027Thermolysin40
- C12Y 304/24075Lysostaphin36
- C12Y 304/24017Stromelysin 127
- C12Y 304/24035Gelatinase b , i.e. matrix metalloprotease 9 or mmp926
All 84 subgroupsShow fewer
- C12Y 304/24065Macrophage elastase , i.e. metalloelastase26
- C12Y 304/24029Aureolysin21
- C12Y 304/24011Neprilysin , i.e. enkephalinase or neutral endopeptidase 24.1119
- C12Y 304/24004Microbial metalloproteinases17
- C12Y 304/24071Endothelin-converting enzyme 117
- C12Y 304/24028Bacillolysin13
- C12Y 304/24068Tentoxilysin , i.e. tetanus neurotoxin13
- C12Y 304/24024Gelatinase a , i.e. matrix metalloproteinase 2 or mmp212
- C12Y 304/24086Adam 17 endopeptidase , i.e. tnf-alpha converting enyzme12
- C12Y 304/24039Deuterolysin10
- C12Y 304/24023Matrilysin9
- C12Y 304/2404Serralysin8
- C12Y 304/24046Adamalysin7
- C12Y 304/2408Membrane-type matrix metalloproteinase-17
- C12Y 304/24082Adamts-4 endopeptidase , i.e. aggrecanase 16
- C12Y 304/24066Choriolysin l5
- C12Y 304/24081Adam10 endopeptidase5
- C12Y 304/24083Anthrax lethal factor endopeptidase5
- C12Y 304/24034Neutrophil collagenase4
- C12Y 304/24057O-sialoglycoprotein endopeptidase , i.e. glycoprotease4
- C12Y 304/24033Peptidyl-asp metalloendopeptidase3
- C12Y 304/24056Insulysin3
- C12Y 304/24812Adamts5 endopeptidase , i.e. aggrecanase 23
- C12Y 304/24014Procollagen n-endopeptidase2
- C12Y 304/24016Neurolysin2
- C12Y 304/24079Pappalysin-12
- C12Y 304/24013Iga-specific metalloendopeptidase1
- C12Y 304/24019Procollagen c-endopeptidase1
- C12Y 304/24022Stromelysin 21
- C12Y 304/24031Mycolysin1
- C12Y 304/24032Beta-lytic metalloendopeptidase1
- C12Y 304/24037Saccharolysin , i.e. yeast cysteine proteinase d1
- C12Y 304/24038Gametolysin , i.e. cell wall lytic enzyme1
- C12Y 304/24061Nardilysin1
- C12Y 304/24067Choriolysin h1
- C12Y 304/24001Atrolysin a0
- C12Y 304/24005Lens neutral proteinase0
- C12Y 304/24006Leucolysin0
- C12Y 304/24012Envelysin0
- C12Y 304/24015Thimet oligopeptidase0
- C12Y 304/24018Meprin a0
- C12Y 304/2402Peptidyl-lys metalloendopeptidase0
- C12Y 304/24021Astacin0
- C12Y 304/24025Vibriolysin0
- C12Y 304/24026Pseudolysin0
- C12Y 304/2403Coccolysin0
- C12Y 304/24036Leishmanolysin0
- C12Y 304/24041Atrolysin b0
- C12Y 304/24042Atrolysin c0
- C12Y 304/24043Atroxase0
- C12Y 304/24044Atrolysin e0
- C12Y 304/24045Atrolysin f0
- C12Y 304/24047Horrilysin0
- C12Y 304/24048Ruberlysin0
- C12Y 304/24049Bothropasin0
- C12Y 304/2405Bothrolysin0
- C12Y 304/24051Ophiolysin0
- C12Y 304/24052Trimerelysin i0
- C12Y 304/24053Trimerelysin ii0
- C12Y 304/24054Mucrolysin0
- C12Y 304/24055Pitrilysin0
- C12Y 304/24058Russellysin0
- C12Y 304/24059Mitochondrial intermediate peptidase0
- C12Y 304/2406Dactylysin0
- C12Y 304/24062Magnolysin0
- C12Y 304/24063Meprin b0
- C12Y 304/24064Mitochondrial processing peptidase0
- C12Y 304/2407Oligopeptidase a0
- C12Y 304/24072Fibrolase0
- C12Y 304/24073Jararhagin0
- C12Y 304/24074Fragilysin0
- C12Y 304/24076Flavastacin0
- C12Y 304/24077Snapalysin0
- C12Y 304/24078Gpr endopeptidase0
- C12Y 304/24084Ste24 endopeptidase0
- C12Y 304/24085S2p endopeptidase0
Recent patents
- Collagenase agent and use thereof29 Sep 2026US 12,747,435 B2Amano Enzyme Inc.
- Method for analyzing protein29 Sep 2026US 12,747,465 B2Hitachi, Ltd.
- Injectable botulinum toxin formulations and methods of use thereof having long duration of therapeutic or cosmetic effect15 Sep 2026US 12,734,226 B2Revance Therapeutics, Inc.
- Mutant protease and use thereof15 Sep 2026US 12,735,692 B2Kao Corporation
- Treatment of brain damage18 Aug 2026US 12,708,661 B2Ipsen Biopharm Ltd.
- Stabilized liquid and lyophilized adamts13 formulations8 Oct 2026US 2026/0306593 A1Takeda Pharmaceutical Company Limited
- Adamts13 protein variants and uses thereof8 Oct 2026US 2026/0308560 A1Sanquin IP B.V.
- Methods Of Treating Plantar Fibromatosis1 Oct 2026US 2026/0295023 A1
- Injection paradigm for administration of botulinum toxins24 Sep 2026US 2026/0284158 A1Allergan, Inc.
- Injection paradigm for administration of botulinum toxins24 Sep 2026US 2026/0284159 A1Allergan, Inc.
Most cited
By later US patents
- 2'deoxy-2'-alkylnucleotide containing nucleic acid521US 5,627,053 ARibozyme Pharmaceuticals, Inc. · 1997
- Immunotherapy against several tumors, such as lung cancer, including NSCLC198US 10,071,148 B2Immatics Biotechnologies GmbH · 2018
- RNA polymerase III-based expression of therapeutic RNAs154US 5,902,880 ARibozyme Pharmaceuticals, Inc. · 1999
- Immunotherapy against several tumors, such as lung cancer, including NSCLC131US 9,943,579 B2Immatics Biotechnologies GmbH · 2018
- 2'-O-alkylthioalkyl and 2-C-alkylthioalkyl-containing enzymatic nucleic acids (ribozymes)127US 5,716,824 ARibozyme Pharmaceuticals, Inc. · 1998