C12N 9/0046
With oxygen as acceptor
Official title: {with oxygen as acceptor (1.7.3)}
C12N9/0046 (With oxygen as acceptor) appears on 70 US grants and 95 published applications in this corpus.
Search patents in C12N- Granted patents
- 70
- Published applications
- 95
- Assignees
- 60
- Inventors
- 247
- Latest grant
- 25 Aug 2026
Filings by year
| Year | Granted patents | Published applications |
|---|---|---|
| 1977 | 2 | 0 |
| 1978 | 0 | 0 |
| 1979 | 0 | 0 |
| 1980 | 1 | 0 |
| 1981 | 1 | 0 |
| 1982 | 1 | 0 |
| 1983 | 2 | 0 |
| 1984 | 0 | 0 |
| 1985 | 0 | 0 |
| 1986 | 0 | 0 |
| 1987 | 0 | 0 |
| 1988 | 0 | 0 |
| 1989 | 1 | 0 |
| 1990 | 0 | 0 |
| 1991 | 1 | 0 |
| 1992 | 1 | 0 |
| 1993 | 1 | 0 |
| 1994 | 1 | 0 |
| 1995 | 2 | 0 |
| 1996 | 1 | 0 |
| 1997 | 1 | 0 |
| 1998 | 5 | 0 |
| 1999 | 1 | 0 |
| 2000 | 0 | 0 |
| 2001 | 0 | 0 |
| 2002 | 0 | 0 |
| 2003 | 2 | 2 |
| 2004 | 1 | 0 |
| 2005 | 1 | 2 |
| 2006 | 1 | 1 |
| 2007 | 0 | 0 |
| 2008 | 0 | 3 |
| 2009 | 0 | 3 |
| 2010 | 3 | 4 |
| 2011 | 5 | 5 |
| 2012 | 4 | 7 |
| 2013 | 4 | 3 |
| 2014 | 1 | 3 |
| 2015 | 3 | 2 |
| 2016 | 1 | 1 |
| 2017 | 2 | 7 |
| 2018 | 4 | 4 |
| 2019 | 1 | 5 |
| 2020 | 2 | 4 |
| 2021 | 4 | 3 |
| 2022 | 1 | 5 |
| 2023 | 2 | 12 |
| 2024 | 1 | 7 |
| 2025 | 0 | 4 |
| 2026 | 5 | 8 |
By publication year. Applications have been published since 2001. 2026 runs to 8 Oct.
Subgroups
Granted patents
Recent patents
- Method for preparing polyethylene glycol-modified urate oxidase25 Aug 2026US 12,714,741 B2Hangzhou Grand Biologic Pharmaceutical Inc.
- Therapeutic engineered microbial cell system and methods for treating hyperuricemia and gout11 Aug 2026US 12,703,849 B2Unlocked Labs
- Methods of treating diseases associated with elevated uric acid11 Aug 2026US 12,703,857 B2Protalix Ltd.
- Modified uricase and uses thereof7 Jul 2026US 12,674,146 B2Protalix Ltd.
- Urate oxidase-albumin conjugate, preparation method thereof, and use thereof12 May 2026US 12,622,951 B2Proabtech Inc.
- Novel uricase variants and methods of use thereof8 Oct 2026US 2026/0308536 A1Insmed Incorporated
- Modified uricase and uses thereof24 Sep 2026US 2026/0286318 A1Protalix Ltd.
- Composition and Method for Synthesizing Pegylated Uricase-Drug Conjugates to Mitigate Anti-Drug Antibody and Their Therapeutic Use27 Aug 2026US 2026/0248931 A1Oncoc4, Inc.
- Nitrification inhibitors30 Jul 2026US 2026/0215425 A1
- Uricase conjugates and methods of use thereof16 Jul 2026US 2026/0201346 A1
Most cited
By later US patents
- PEG-urate oxidase conjugates and use thereof100US 6,576,235 B1Duke University · 2003
- Aggregate-free urate oxidase for preparation of non-immunogenic polymer conjugates95US 6,783,965 B1Mountain View Pharmaceuticals, Inc. · 2004
- Somatic gene therapy to cells associated with fluid spaces87US 5,770,580 ABaylor College of Medicine · 1998
- PEG-modified uricase78US 6,913,915 B2Phoenix Pharmacologics, Inc. · 2005
- Tranformation of cells associated with fluid spaces45US 5,792,751 ABaylor College of Medicine · 1998