C12N 2320/13
In a process of directed evolution
Official title: in a process of directed evolution, e.g. SELEX, acquiring a new function
C12N2320/13 (In a process of directed evolution) appears on 103 US grants and 181 published applications in this corpus.
Search patents in C12N- Granted patents
- 103
- Published applications
- 181
- Assignees
- 128
- Inventors
- 434
- Latest grant
- 11 Aug 2026
Filings by year
| Year | Granted patents | Published applications |
|---|---|---|
| 1998 | 3 | 0 |
| 1999 | 2 | 0 |
| 2000 | 0 | 0 |
| 2001 | 2 | 0 |
| 2002 | 0 | 0 |
| 2003 | 0 | 1 |
| 2004 | 0 | 2 |
| 2005 | 0 | 3 |
| 2006 | 0 | 4 |
| 2007 | 0 | 3 |
| 2008 | 2 | 1 |
| 2009 | 2 | 6 |
| 2010 | 0 | 3 |
| 2011 | 1 | 5 |
| 2012 | 2 | 2 |
| 2013 | 6 | 5 |
| 2014 | 3 | 7 |
| 2015 | 3 | 9 |
| 2016 | 3 | 14 |
| 2017 | 6 | 10 |
| 2018 | 15 | 11 |
| 2019 | 7 | 14 |
| 2020 | 5 | 8 |
| 2021 | 10 | 22 |
| 2022 | 4 | 17 |
| 2023 | 6 | 11 |
| 2024 | 3 | 7 |
| 2025 | 10 | 10 |
| 2026 | 8 | 6 |
By publication year. Applications have been published since 2001. 2026 runs to 8 Oct.
Recent patents
- Monocyte-specific aptamers and uses thereof for delivering therapeutic agents to heart11 Aug 2026US 12,702,716 B2Academia Sinica
- Methods and compositions for rapid direct detection and differentiation of infectious from noninfectious virus11 Aug 2026US 12,704,516 B2Consejo Nacional De Investigaciones Cientificas Y Tecnicas
- Targeted mutagenesis using base editors28 Apr 2026US 12,612,622 B2Qi Biodesign Biotechnology Company Limited
- Method for selecting aptamers with high target specificity in a microfluidic device platform for co-culture of multiple tissues3 Mar 2026US 12,565,675 B2Bioptamers Pesquisa E Desenvolvimento Ltda
- Methods and compositions for selection of functional aptamers10 Feb 2026US 12,545,906 B2Aummune Ltd.
- Bio-fluid's ligand library enrichment technology and uses thereof27 Aug 2026US 2026/0250660 A1Eisai R&D Management Co., Ltd.
- Aptamers for the detection of drugs, biomarkers, and small molecules for ocular applications13 Aug 2026US 2026/0234640 A1Centre for Eye and Vision Research Limited
- Method of SElection with Modified Aptamers (SELMA) Enabling Incorporation of Fluorinated or Methoxylated RNA6 Aug 2026US 2026/0226453 A1Brandeis University
- Methods for producing soybean with altered composition23 Jul 2026US 2026/0206701 A1Pioneer Hi-Bred International, Inc.
- Aptamers Against Clostridium Difficile2 Jul 2026US 2026/0185105 A1Liv Process, Inc.
Most cited
By later US patents
- Enzymatic DNA molecules179US 6,326,174 B1The Scripps Research Institute · 2001
- Systematic evolution of ligands by exponential enrichment: tissue selex104US 5,712,375 ANeXstar Pharmaceuticals, Inc. · 1998
- Enzymatic DNA molecules85US 5,807,718 AThe Scripps Research Institute · 1998
- Method for obtaining oligonucleotide aptamers and uses thereof81US 8,492,082 B2Consiglio Nazionale Delle Richerche · 2013
- Systematic evolution of ligands by exponential enrichment: tissue selex65US 5,864,026 ANeXstar Pharmaceuticals, Inc. · 1999