C07K 1/113
Without change of the primary structure
Official title: without change of the primary structure
C07K1/113 (Without change of the primary structure) appears on 602 US grants and 644 published applications in this corpus.
Search patents in C07K- Granted patents
- 602
- Published applications
- 644
- Assignees
- 348
- Inventors
- 1,477
- Latest grant
- 15 Sep 2026
Filings by year
| Year | Granted patents | Published applications |
|---|---|---|
| 1977 | 1 | 0 |
| 1978 | 0 | 0 |
| 1979 | 0 | 0 |
| 1980 | 0 | 0 |
| 1981 | 0 | 0 |
| 1982 | 1 | 0 |
| 1983 | 1 | 0 |
| 1984 | 3 | 0 |
| 1985 | 5 | 0 |
| 1986 | 4 | 0 |
| 1987 | 8 | 0 |
| 1988 | 11 | 0 |
| 1989 | 4 | 0 |
| 1990 | 16 | 0 |
| 1991 | 11 | 0 |
| 1992 | 14 | 0 |
| 1993 | 10 | 0 |
| 1994 | 12 | 0 |
| 1995 | 9 | 0 |
| 1996 | 8 | 0 |
| 1997 | 19 | 0 |
| 1998 | 23 | 0 |
| 1999 | 19 | 0 |
| 2000 | 13 | 0 |
| 2001 | 11 | 1 |
| 2002 | 10 | 30 |
| 2003 | 21 | 22 |
| 2004 | 13 | 19 |
| 2005 | 8 | 23 |
| 2006 | 12 | 17 |
| 2007 | 10 | 16 |
| 2008 | 6 | 25 |
| 2009 | 10 | 23 |
| 2010 | 14 | 25 |
| 2011 | 13 | 22 |
| 2012 | 8 | 16 |
| 2013 | 10 | 26 |
| 2014 | 26 | 37 |
| 2015 | 28 | 28 |
| 2016 | 21 | 31 |
| 2017 | 15 | 34 |
| 2018 | 18 | 23 |
| 2019 | 23 | 27 |
| 2020 | 16 | 22 |
| 2021 | 29 | 32 |
| 2022 | 27 | 42 |
| 2023 | 19 | 31 |
| 2024 | 18 | 34 |
| 2025 | 16 | 24 |
| 2026 | 8 | 14 |
By publication year. Applications have been published since 2001. 2026 runs to 8 Oct.
Subgroups
Granted patents
Recent patents
- Cyclic peptide and preparation method and use thereof15 Sep 2026US 12,735,456 B2Hangzhou Huibo Science and Technology Co., Ltd
- Sulfur extrusion from disulfides by carbenes25 Aug 2026US 12,715,895 B2Universität Heidelberg
- Process for preparing a GIP/GLP1 dual agonist25 Aug 2026US 12,715,901 B2Eli Lilly and Company
- Process for preparing a GIP/GLP1 dual agonist19 May 2026US 12,630,601 B2Eli Lilly and Company
- Compositions and methods for modification of target molecules12 May 2026US 12,624,063 B2The Regents of the University of California
- Native peptide cyclization, sequential chemoselective amidation in water8 Oct 2026US 2026/0308200 A1The Research Foundation for The State University of New York
- Anti-vegf protein compositions and methods for producing the same8 Oct 2026US 2026/0308231 A1Regeneron Pharmaceuticals, Inc.
- Anti-vegf protein compositions and methods for producing the same8 Oct 2026US 2026/0308232 A1Regeneron Pharmaceuticals, Inc.
- Anti-vegf protein compositions and methods for producing the same8 Oct 2026US 2026/0308233 A1Regeneron Pharmaceuticals, Inc.
- Anti-vegf protein compositions and methods for producing the same24 Sep 2026US 2026/0285940 A1Regeneron Pharmaceuticals, Inc.
Most cited
By later US patents
- Process for bacterial production of polypeptides265US 5,789,199 AGenentech, Inc. · 1998
- Purification and activity assurance of precipitated heterologous proteins229US 4,511,503 AGenentech, Inc. · 1985
- Purification and activity assurance of precipitated heterologous proteins212US 4,511,502 AGenentech, Inc. · 1985
- Purification and activity assurance of precipitated heterologous proteins206US 4,512,922 AGenentech, Inc. · 1985
- Synthesis of conformationally restricted amino acids, peptides, and peptidomimetics by catalytic ring closing metathesis162US 5,811,515 ACalifornia Institute of Technology · 1998