C07D 451/12
Acylated by aromatic or heteroaromatic carboxylic acids
Official title: acylated by aromatic or heteroaromatic carboxylic acids, e.g. cocaine
C07D451/12 (Acylated by aromatic or heteroaromatic carboxylic acids) appears on 88 US grants and 52 published applications in this corpus.
Search patents in C07D- Granted patents
- 88
- Published applications
- 52
- Assignees
- 45
- Inventors
- 179
- Latest grant
- 19 May 2026
Filings by year
| Year | Granted patents | Published applications |
|---|---|---|
| 1977 | 2 | 0 |
| 1978 | 3 | 0 |
| 1979 | 0 | 0 |
| 1980 | 0 | 0 |
| 1981 | 0 | 0 |
| 1982 | 0 | 0 |
| 1983 | 0 | 0 |
| 1984 | 1 | 0 |
| 1985 | 1 | 0 |
| 1986 | 1 | 0 |
| 1987 | 0 | 0 |
| 1988 | 1 | 0 |
| 1989 | 4 | 0 |
| 1990 | 3 | 0 |
| 1991 | 5 | 0 |
| 1992 | 1 | 0 |
| 1993 | 6 | 0 |
| 1994 | 5 | 0 |
| 1995 | 3 | 0 |
| 1996 | 7 | 0 |
| 1997 | 1 | 0 |
| 1998 | 3 | 0 |
| 1999 | 1 | 0 |
| 2000 | 1 | 0 |
| 2001 | 4 | 0 |
| 2002 | 3 | 1 |
| 2003 | 0 | 3 |
| 2004 | 1 | 2 |
| 2005 | 0 | 2 |
| 2006 | 1 | 0 |
| 2007 | 1 | 3 |
| 2008 | 1 | 1 |
| 2009 | 0 | 0 |
| 2010 | 2 | 4 |
| 2011 | 1 | 0 |
| 2012 | 2 | 2 |
| 2013 | 1 | 2 |
| 2014 | 2 | 6 |
| 2015 | 2 | 2 |
| 2016 | 2 | 3 |
| 2017 | 2 | 7 |
| 2018 | 6 | 5 |
| 2019 | 4 | 4 |
| 2020 | 1 | 1 |
| 2021 | 0 | 1 |
| 2022 | 1 | 2 |
| 2023 | 0 | 0 |
| 2024 | 0 | 0 |
| 2025 | 1 | 0 |
| 2026 | 1 | 1 |
By publication year. Applications have been published since 2001. 2026 runs to 8 Oct.
Recent patents
- Method for introducing deuterated lower alkyl into amine moiety of compound containing secondary amine19 May 2026US 12,630,487 B2Otsuka Pharmaceutical Co., Ltd.
- Molecules that stimulate the immune system for treatment of drug addiction, methods of synthesis, antidrug vaccine and uses6 May 2025US 12,291,527 B2Fundacao De Amparo A Pesquisa Do Estado De Minas Gerais-Fapemig
- Tropinol esters and related compounds to promote normal processing of APP10 May 2022US 11,325,904 B2Buck Institute for Research on Aging
- Therapeutic compound for pain and synthesis thereof8 Sep 2020US 10,766,898 B2Janssen Pharmaceutica NV
- 5-HT3 receptor antagonists10 Sep 2019US 10,407,443 B2Takeda Pharmaceutical Company Limited
- Universal solid supports and phosphoramidite building blocks for oligonucleotide synthesis7 May 2026US 2026/0125413 A1AM Chemicals LLC
- Compositions and methods for the treatment of anal and rectal disorders13 Oct 2022US 2022/0324813 A1Cellix Bio Private Limited
- Method for introducing deuterated lower alkyl into amine moiety of compound containing secondary amine28 Apr 2022US 2022/0127206 A1Otsuka Pharmaceutical Co., Ltd.
- Preparation of (-)-cocaine hydrochloride11 Mar 2021US 2021/0069173 A1Cody Laboratories, Inc.
- Molecules that stimulate the immune system for treatment of drug addiction, methods of synthesis, antidrug vaccine and uses10 Dec 2020US 2020/0385376 A1Fundacao De Amparo A Pesquisa Do Estado De Minas Gerais-Fapemig
Most cited
By later US patents
- Use of certain imidazol carbazols in treating stress-related manic-depressive disorders90US 5,561,149 ASandoz Ltd. · 1996
- Heterocyclic carboxylic acid amides and esters58US 4,789,673 A1988
- 1-acyl indazoles56US 4,937,247 ABeecham Group Limited · 1990
- Indazolyl carboxylic acid amides useful for treating migraine clusters headache, trigeminal neuralgia or emesis52US 4,886,808 ABeecham Group Limited · 1989
- 1H-indazole-3-carboxamide-N-2-azabicyclo[2.2.2]octanes useful for treating anxiety, psychosis, neuralgia, migraine and cluster headaches47US 5,034,398 ABeecham Group Limited · 1991