C07D 451/06
Oxygen atoms
C07D451/06 (Oxygen atoms) appears on 552 US grants and 542 published applications in this corpus.
Search patents in C07D- Granted patents
- 552
- Published applications
- 542
- Assignees
- 280
- Inventors
- 1,592
- Latest grant
- 14 Jul 2026
Filings by year
| Year | Granted patents | Published applications |
|---|---|---|
| 1976 | 1 | 0 |
| 1977 | 4 | 0 |
| 1978 | 4 | 0 |
| 1979 | 0 | 0 |
| 1980 | 3 | 0 |
| 1981 | 1 | 0 |
| 1982 | 2 | 0 |
| 1983 | 2 | 0 |
| 1984 | 3 | 0 |
| 1985 | 4 | 0 |
| 1986 | 4 | 0 |
| 1987 | 2 | 0 |
| 1988 | 6 | 0 |
| 1989 | 6 | 0 |
| 1990 | 7 | 0 |
| 1991 | 8 | 0 |
| 1992 | 3 | 0 |
| 1993 | 11 | 0 |
| 1994 | 9 | 0 |
| 1995 | 10 | 0 |
| 1996 | 12 | 0 |
| 1997 | 15 | 0 |
| 1998 | 14 | 0 |
| 1999 | 8 | 0 |
| 2000 | 9 | 0 |
| 2001 | 17 | 2 |
| 2002 | 8 | 18 |
| 2003 | 16 | 33 |
| 2004 | 20 | 26 |
| 2005 | 11 | 25 |
| 2006 | 9 | 22 |
| 2007 | 11 | 31 |
| 2008 | 13 | 23 |
| 2009 | 23 | 31 |
| 2010 | 12 | 34 |
| 2011 | 26 | 26 |
| 2012 | 22 | 25 |
| 2013 | 22 | 31 |
| 2014 | 36 | 36 |
| 2015 | 27 | 20 |
| 2016 | 20 | 18 |
| 2017 | 18 | 18 |
| 2018 | 11 | 17 |
| 2019 | 17 | 12 |
| 2020 | 10 | 11 |
| 2021 | 7 | 20 |
| 2022 | 10 | 15 |
| 2023 | 9 | 25 |
| 2024 | 6 | 9 |
| 2025 | 13 | 6 |
| 2026 | 10 | 8 |
By publication year. Applications have been published since 2001. 2026 runs to 8 Oct.
Subgroups
Granted patents
Recent patents
- Compositions and methods for the treatment of liver disorders14 Jul 2026US 12,678,430 B2Viking Therapeutics, Inc.
- FXR small-molecule agonist, and preparation method therefor and use thereof16 Jun 2026US 12,655,148 B2Shanghai Institute of Materia Medica, Chinese Academy of Sciences
- Method for introducing deuterated lower alkyl into amine moiety of compound containing secondary amine19 May 2026US 12,630,487 B2Otsuka Pharmaceutical Co., Ltd.
- Inhibitors of RIPK2 and medical uses thereof12 May 2026US 12,624,018 B1Odyssey Therapeutics, Inc.
- Sigma-1 receptor ligands and therapeutic uses thereof28 Apr 2026US 12,612,371 B2Centre National De La Recherche Scientifique
- Flow chemistry process for preparing aza-bicyclic heteroaryl compounds20 Aug 2026US 2026/0242370 A1Actinogen Medical Limited
- Inhibitors of ripk2 and medical uses thereof25 Jun 2026US 2026/0176251 A1Odyssey Therapeutics, Inc.
- Hdac6 inhibitors and uses thereof18 Jun 2026US 2026/0167604 A1Eikonizo Therapeutics, Inc.
- Inhibitors of ripk2 and medical uses thereof14 May 2026US 2026/0132121 A1Odyssey Therapeutics, Inc.
- Universal solid supports and phosphoramidite building blocks for oligonucleotide synthesis7 May 2026US 2026/0125413 A1AM Chemicals LLC
Most cited
By later US patents
- 4-pyrazolyl-N-arylpyrimidin-2-amines and 4-pyrazolyl-N-heteroarylpyrimidin-2-amines as janus kinase inhibitors109US 8,309,718 B2Incyte Corporation · 2012
- Use of certain imidazol carbazols in treating stress-related manic-depressive disorders90US 5,561,149 ASandoz Ltd. · 1996
- Esters of thienyl carboxylic acids and amino alcohols and their quaternization products87US 5,610,163 ABoehringer Ingelheim GmbH · 1997
- Pyrimidine derivatives79US 7,173,028 B2Boehringer Ingelheim Pharma GMBH & CO.KG · 2007
- Selective estrogen receptor modulator79US 7,612,114 B2Eisai R&D Management Co., Ltd. · 2009