C07D 451/02
Containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring
Official title: containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
C07D451/02 (Containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring) appears on 1,479 US grants and 1,500 published applications in this corpus.
Search patents in C07D- Granted patents
- 1,479
- Published applications
- 1,500
- Assignees
- 634
- Inventors
- 4,662
- Latest grant
- 6 Oct 2026
Filings by year
| Year | Granted patents | Published applications |
|---|---|---|
| 1976 | 2 | 0 |
| 1977 | 7 | 0 |
| 1978 | 4 | 0 |
| 1979 | 4 | 0 |
| 1980 | 6 | 0 |
| 1981 | 3 | 0 |
| 1982 | 7 | 0 |
| 1983 | 5 | 0 |
| 1984 | 10 | 0 |
| 1985 | 7 | 0 |
| 1986 | 10 | 0 |
| 1987 | 4 | 0 |
| 1988 | 9 | 0 |
| 1989 | 19 | 0 |
| 1990 | 19 | 0 |
| 1991 | 15 | 0 |
| 1992 | 10 | 0 |
| 1993 | 28 | 0 |
| 1994 | 26 | 0 |
| 1995 | 25 | 0 |
| 1996 | 28 | 0 |
| 1997 | 38 | 0 |
| 1998 | 34 | 0 |
| 1999 | 28 | 0 |
| 2000 | 25 | 0 |
| 2001 | 42 | 7 |
| 2002 | 26 | 38 |
| 2003 | 41 | 58 |
| 2004 | 32 | 63 |
| 2005 | 18 | 63 |
| 2006 | 25 | 76 |
| 2007 | 39 | 69 |
| 2008 | 44 | 72 |
| 2009 | 64 | 80 |
| 2010 | 47 | 88 |
| 2011 | 61 | 69 |
| 2012 | 54 | 51 |
| 2013 | 61 | 65 |
| 2014 | 65 | 76 |
| 2015 | 60 | 57 |
| 2016 | 47 | 52 |
| 2017 | 42 | 57 |
| 2018 | 42 | 56 |
| 2019 | 51 | 58 |
| 2020 | 46 | 53 |
| 2021 | 40 | 52 |
| 2022 | 40 | 57 |
| 2023 | 29 | 71 |
| 2024 | 31 | 50 |
| 2025 | 38 | 32 |
| 2026 | 21 | 30 |
By publication year. Applications have been published since 2001. 2026 runs to 8 Oct.
Subgroups
Granted patents
Recent patents
- Diaminopyrimidine carboxamide inhibitors of HPK16 Oct 2026US 12,753,163 B2Merck Sharp & Dohme Corp.
- Quinoxaline derivatives and uses thereof22 Sep 2026US 12,741,976 B2Black Diamond Therapeutics, Inc.
- Antimicrobial compounds and methods28 Jul 2026US 12,692,253 B2Curza Global, LLC
- Compositions and methods for the treatment of liver disorders14 Jul 2026US 12,678,430 B2Viking Therapeutics, Inc.
- Substituted pyrazole compounds and methods of using them for treatment of hyperproliferative diseases23 Jun 2026US 12,662,477 B2Bantam Pharmaceutical, LLC
- Oxazole trpml1 agonists and uses thereof1 Oct 2026US 2026/0297104 A1Libra Therapeutics, Inc.
- Sulfamide derivatives as cyclin-dependent kinase 2 inhibitors17 Sep 2026US 2026/0274833 A1Nikang Therapeutics, Inc.
- Heterocyclic compounds as 5ht2a biased agonists10 Sep 2026US 2026/0265246 A1
- Heteroaryl enhancers of the particulate guanylyl cyclase receptor a27 Aug 2026US 2026/0250275 A1University of Florida Research Foundation, Inc.
- Flow chemistry process for preparing aza-bicyclic heteroaryl compounds20 Aug 2026US 2026/0242370 A1Actinogen Medical Limited
Most cited
By later US patents
- Urea derivatives and their use as ACAT inhibitors134US 5,621,010 ANisshin Flour Milling Co., Ltd. · 1997
- 4-pyrazolyl-N-arylpyrimidin-2-amines and 4-pyrazolyl-N-heteroarylpyrimidin-2-amines as janus kinase inhibitors109US 8,309,718 B2Incyte Corporation · 2012
- Pharmaceutical compositions of 3-(6-(1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl) cyclopropanecarboxamido)-3-methylpyridin-2-yl)benzoic acid and administration thereof95US 8,552,034 B2Vertex Pharmaceuticals Incorporated · 2013
- Use of certain imidazol carbazols in treating stress-related manic-depressive disorders90US 5,561,149 ASandoz Ltd. · 1996
- Esters of thienyl carboxylic acids and amino alcohols and their quaternization products87US 5,610,163 ABoehringer Ingelheim GmbH · 1997