C07D 451/04
With hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1]
Official title: with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
C07D451/04 (With hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1]) appears on 958 US grants and 931 published applications in this corpus.
Search patents in C07D- Granted patents
- 958
- Published applications
- 931
- Assignees
- 450
- Inventors
- 2,925
- Latest grant
- 28 Jul 2026
Filings by year
| Year | Granted patents | Published applications |
|---|---|---|
| 1976 | 1 | 0 |
| 1977 | 4 | 0 |
| 1978 | 4 | 0 |
| 1979 | 0 | 0 |
| 1980 | 3 | 0 |
| 1981 | 2 | 0 |
| 1982 | 7 | 0 |
| 1983 | 4 | 0 |
| 1984 | 8 | 0 |
| 1985 | 7 | 0 |
| 1986 | 8 | 0 |
| 1987 | 3 | 0 |
| 1988 | 8 | 0 |
| 1989 | 15 | 0 |
| 1990 | 16 | 0 |
| 1991 | 13 | 0 |
| 1992 | 7 | 0 |
| 1993 | 20 | 0 |
| 1994 | 18 | 0 |
| 1995 | 17 | 0 |
| 1996 | 22 | 0 |
| 1997 | 30 | 0 |
| 1998 | 20 | 0 |
| 1999 | 14 | 0 |
| 2000 | 16 | 0 |
| 2001 | 25 | 3 |
| 2002 | 13 | 25 |
| 2003 | 23 | 34 |
| 2004 | 23 | 38 |
| 2005 | 12 | 46 |
| 2006 | 13 | 41 |
| 2007 | 21 | 48 |
| 2008 | 31 | 47 |
| 2009 | 39 | 56 |
| 2010 | 32 | 61 |
| 2011 | 44 | 49 |
| 2012 | 40 | 32 |
| 2013 | 36 | 43 |
| 2014 | 47 | 52 |
| 2015 | 40 | 36 |
| 2016 | 32 | 31 |
| 2017 | 29 | 34 |
| 2018 | 22 | 34 |
| 2019 | 32 | 25 |
| 2020 | 23 | 29 |
| 2021 | 20 | 31 |
| 2022 | 20 | 29 |
| 2023 | 17 | 45 |
| 2024 | 18 | 31 |
| 2025 | 25 | 17 |
| 2026 | 14 | 14 |
By publication year. Applications have been published since 2001. 2026 runs to 8 Oct.
Subgroups
Granted patents
Recent patents
- Antimicrobial compounds and methods28 Jul 2026US 12,692,253 B2Curza Global, LLC
- Compositions and methods for the treatment of liver disorders14 Jul 2026US 12,678,430 B2Viking Therapeutics, Inc.
- FXR small-molecule agonist, and preparation method therefor and use thereof16 Jun 2026US 12,655,148 B2Shanghai Institute of Materia Medica, Chinese Academy of Sciences
- Method for introducing deuterated lower alkyl into amine moiety of compound containing secondary amine19 May 2026US 12,630,487 B2Otsuka Pharmaceutical Co., Ltd.
- Inhibitors of RIPK2 and medical uses thereof12 May 2026US 12,624,018 B1Odyssey Therapeutics, Inc.
- Sulfamide derivatives as cyclin-dependent kinase 2 inhibitors17 Sep 2026US 2026/0274833 A1Nikang Therapeutics, Inc.
- Flow chemistry process for preparing aza-bicyclic heteroaryl compounds20 Aug 2026US 2026/0242370 A1Actinogen Medical Limited
- Inhibitors of ripk2 and medical uses thereof25 Jun 2026US 2026/0176251 A1Odyssey Therapeutics, Inc.
- Hdac6 inhibitors and uses thereof18 Jun 2026US 2026/0167604 A1Eikonizo Therapeutics, Inc.
- Bifunctional compounds containing 2,5-substituted pyrimidine derivatives for degrading cyclin-dependent kinase 2 via ubiquitin proteasome pathway18 Jun 2026US 2026/0167623 A1Nikang Therapeutics, Inc.
Most cited
By later US patents
- Urea derivatives and their use as ACAT inhibitors134US 5,621,010 ANisshin Flour Milling Co., Ltd. · 1997
- 4-pyrazolyl-N-arylpyrimidin-2-amines and 4-pyrazolyl-N-heteroarylpyrimidin-2-amines as janus kinase inhibitors109US 8,309,718 B2Incyte Corporation · 2012
- Use of certain imidazol carbazols in treating stress-related manic-depressive disorders90US 5,561,149 ASandoz Ltd. · 1996
- Esters of thienyl carboxylic acids and amino alcohols and their quaternization products87US 5,610,163 ABoehringer Ingelheim GmbH · 1997
- Indoles, 1H-indazoles, 1,2-benzisoxazoles, 1,2-benzoisothiazoles, and preparation and uses thereof85US 7,902,217 B2Memory Pharmaceuticals Corporation · 2011