C07D 451/10
Acylated by aliphatic or araliphatic carboxylic acids
Official title: acylated by aliphatic or araliphatic carboxylic acids, e.g. atropine, scopolamine
C07D451/10 (Acylated by aliphatic or araliphatic carboxylic acids) appears on 111 US grants and 123 published applications in this corpus.
Search patents in C07D- Granted patents
- 111
- Published applications
- 123
- Assignees
- 54
- Inventors
- 231
- Latest grant
- 19 May 2026
Filings by year
| Year | Granted patents | Published applications |
|---|---|---|
| 1976 | 1 | 0 |
| 1977 | 1 | 0 |
| 1978 | 0 | 0 |
| 1979 | 0 | 0 |
| 1980 | 1 | 0 |
| 1981 | 0 | 0 |
| 1982 | 0 | 0 |
| 1983 | 1 | 0 |
| 1984 | 1 | 0 |
| 1985 | 2 | 0 |
| 1986 | 0 | 0 |
| 1987 | 1 | 0 |
| 1988 | 1 | 0 |
| 1989 | 0 | 0 |
| 1990 | 1 | 0 |
| 1991 | 1 | 0 |
| 1992 | 1 | 0 |
| 1993 | 2 | 0 |
| 1994 | 1 | 0 |
| 1995 | 1 | 0 |
| 1996 | 1 | 0 |
| 1997 | 5 | 0 |
| 1998 | 2 | 0 |
| 1999 | 2 | 0 |
| 2000 | 0 | 0 |
| 2001 | 4 | 0 |
| 2002 | 2 | 4 |
| 2003 | 3 | 13 |
| 2004 | 7 | 6 |
| 2005 | 3 | 10 |
| 2006 | 2 | 5 |
| 2007 | 4 | 7 |
| 2008 | 5 | 4 |
| 2009 | 5 | 5 |
| 2010 | 1 | 7 |
| 2011 | 4 | 3 |
| 2012 | 5 | 10 |
| 2013 | 2 | 4 |
| 2014 | 8 | 7 |
| 2015 | 6 | 6 |
| 2016 | 0 | 2 |
| 2017 | 3 | 6 |
| 2018 | 5 | 4 |
| 2019 | 3 | 1 |
| 2020 | 1 | 2 |
| 2021 | 0 | 3 |
| 2022 | 3 | 5 |
| 2023 | 1 | 3 |
| 2024 | 2 | 2 |
| 2025 | 4 | 3 |
| 2026 | 2 | 1 |
By publication year. Applications have been published since 2001. 2026 runs to 8 Oct.
Recent patents
- Method for introducing deuterated lower alkyl into amine moiety of compound containing secondary amine19 May 2026US 12,630,487 B2Otsuka Pharmaceutical Co., Ltd.
- Aqueous pharmaceutical compositions comprising benzyl atropine and uses thereof20 Jan 2026US 12,527,739 B2Alcon Inc.
- Itaconic acid derivatives and uses thereof intreating an inflammatory disease or a disease associated with an undesirable immune response19 Aug 2025US 12,390,437 B2Sitryx Therapeutics Limited
- Method for improving stability of low-concentration atropine ophthalmic preparation20 May 2025US 12,303,500 B2Shenyang Xingqi Pharmaceutical Co., Ltd.
- Synthetic route to scopolamine and/or atropine13 May 2025US 12,297,195 B2Southwest Research Institute
- Universal solid supports and phosphoramidite building blocks for oligonucleotide synthesis7 May 2026US 2026/0125413 A1AM Chemicals LLC
- Synthetic route to scopolamine and/or atropine24 Jul 2025US 2025/0236618 A1Southwest Research Institute
- Ophthalmic composition and delivery device thereof12 Jun 2025US 2025/0186251 A1Sydnexis, Inc.
- Esters of 8-methyl-8-azabicyclo[3.2.1] octan-3-yl 3-hydroxy-2-phenylpropanoate10 Apr 2025US 2025/0115596 A1ADS Therapeutics LLC
- Azabicyclo and diazepine derivatives25 Apr 2024US 2024/0132497 A1Alcon Inc.
Most cited
By later US patents
- Esters of thienyl carboxylic acids and amino alcohols and their quaternization products87US 5,610,163 ABoehringer Ingelheim GmbH · 1997
- Esters of bi- and tricyclic amino alcohols and their use in pharmaceutical compositions77US 5,654,314 ABoehringer Ingelheim GmbH · 1997
- Crystalline tiotropium bromide monohydrate, processes for the preparation thereof, and pharmaceutical compositions72US 6,777,423 B2Boehringer Ingelheim Pharma GMBH & CO.KG · 2004
- Anticholinergics which may be used as medicaments as well as processes for preparing them56US 6,706,726 B2Boehringer Ingelheim Pharma GMBH & CO.KG · 2004
- Crystalline tiotropium bromide monohydrate, processes for the preparation thereof, and pharmaceutical compositions56US 6,908,928 B2BI Pharma KG. · 2005