Anticholinergics which may be used as medicaments as well as processes for preparing them
AssigneeBoehringer Ingelheim Pharma GmbH & Co. KG
InventorsHelmut Meissner, Gerd Morschhaeuser, Michael Paul Pieper, Gerald Pohl, Richard Reichl, Georg Speck, Rolf Banholzer
Life of this patent
Estimating the term…
Abstract
The present invention relates to new anticholinergics of general formula 1: wherein A, X− and the groups R1, R2, R3, R4, R5, R6 and R7 may have the meanings given in the claims and in the specification, processes for preparing them and their use as pharamaceutical compositions.
Claims24
A compound of formula 1:
- wherein:
- A is a group selected from
- X− is an anion with a single negative charge;
- R1 and R2, which are identical or different, are each C1-C4-alkyl, which are optionally substituted by hydroxy or halogen;
- R3, R4, R5, and R6, which are identical or different, are each hydrogen, C1-C4-alkyl, C1-C4-alkyloxy, hydroxy, CF3, CN, NO2, or halogen;
- R7 is C1-C4-alkyl, C1-C4-alkyloxy, C1-C4-alkylene-halogen, halogen-C1-C4-alkyloxy, C1-C4-alkylene-OH, CF3, —C1-C4-alkylene-C1-C4-alkyloxy, —O—COC1-C4-alkyl, —O—COC1-C4-alkyl-halogen, —O—COCF3, or halogen.
Scopine 2,2-diphenylpropionate methobromide.
Scopine 2-fluoro-2,2-diphenylacetate methobromide.
Tropenol 2,2-diphenylpropionate methobromide.
Tropenol 2-fluoro-2,2-bis(3,4-difluorophenyl)acetate methobromide.
Scopine 2,2-diphenylpropionate ethylbromide.
Scopine 2-fluoro-2,2-bis(3,4-difluorophenyl)acetate methobromide.
Tropenol 2-fluoro-2,2-bis(4-fluorophenyl)acetate methobromide.
Scopine 2-fluoro-2,2-bis(4-fluorophenyl)acetate methobromide.
Tropenol 2-fluoro-2,2-diphenylacetate methobromide.
Tropenol 2-fluoro-2,2-(3-chlorophenyl)acetate methobromide.
Dependencies are inferred from the claim text.