B01D 15/305
Hydrophilic interaction chromatography [hilic]
Official title: {Hydrophilic interaction chromatography [HILIC]}
B01D15/305 (Hydrophilic interaction chromatography [hilic]) appears on 88 US grants and 144 published applications in this corpus.
Search patents in B01D- Granted patents
- 88
- Published applications
- 144
- Assignees
- 67
- Inventors
- 246
- Latest grant
- 28 Apr 2026
Filings by year
| Year | Granted patents | Published applications |
|---|---|---|
| 1994 | 1 | 0 |
| 1995 | 1 | 0 |
| 1996 | 0 | 0 |
| 1997 | 1 | 0 |
| 1998 | 0 | 0 |
| 1999 | 1 | 0 |
| 2000 | 0 | 0 |
| 2001 | 1 | 1 |
| 2002 | 0 | 4 |
| 2003 | 1 | 1 |
| 2004 | 2 | 2 |
| 2005 | 2 | 2 |
| 2006 | 2 | 1 |
| 2007 | 2 | 1 |
| 2008 | 2 | 5 |
| 2009 | 2 | 6 |
| 2010 | 2 | 6 |
| 2011 | 2 | 4 |
| 2012 | 1 | 6 |
| 2013 | 3 | 3 |
| 2014 | 2 | 8 |
| 2015 | 1 | 5 |
| 2016 | 4 | 10 |
| 2017 | 3 | 8 |
| 2018 | 6 | 5 |
| 2019 | 7 | 13 |
| 2020 | 5 | 11 |
| 2021 | 7 | 10 |
| 2022 | 7 | 8 |
| 2023 | 7 | 7 |
| 2024 | 6 | 7 |
| 2025 | 3 | 4 |
| 2026 | 4 | 6 |
By publication year. Applications have been published since 2001. 2026 runs to 8 Oct.
Recent patents
- Chromatographic columns and separation devices comprising a superficially porous material; and use thereof for supercritical fluid chromatography and other chromatography28 Apr 2026US 12,611,617 B2Waters Technologies Corporation
- Use of amino acids to enhance signal in mass spectral analyses31 Mar 2026US 12,590,970 B2Regeneron Pharmaceuticals, Inc.
- Separation of nucleic acid component compounds on zwitterionic stationary phases24 Mar 2026US 12,584,159 B2Waters Technologies Corporation
- Temperature-assisted on-column focusing17 Mar 2026US 12,576,344 B2University of Pittsburgh—Of the Commonwealth System of Higher Education
- System and method for characterizing drug product impurities4 Nov 2025US 12,459,986 B2Regeneron Pharmaceuticals, Inc.
- Chromatography column packing material, chromatography column, method for producing chromatography column, chromatography analysis apparatus, and analysis method17 Sep 2026US 2026/0273435 A1AQAS Corporation
- Lc-ms method for analyzing carbon capture solvents and their degradation products13 Aug 2026US 2026/0233123 A1Aramco Services Company
- Quantitative determination method for hex4, lyso-gm1, fuc-glcnac-asn, and lyso-sulfatide included in cerebrospinal fluid14 May 2026US 2026/0133202 A1JCR Pharmaceuticals Co., Ltd.
- Methods of separating chelator26 Mar 2026US 2026/0085108 A1
- Composition of chromatographic sorbents and methods for analysis of antibody drug conjugates12 Mar 2026US 2026/0070001 A1
Most cited
By later US patents
- Use of retentate chromatography to generate difference maps229US 6,225,047 B1Ciphergen Biosystems, Inc. · 2001
- Multimodal chromatographic separation media and process for using same87US 5,316,680 ACornell Research Foundation, Inc. · 1994
- Retentate chromatography and protein chip arrays with applications in biology and medicine61US 6,579,719 B1Ciphergen Biosystems, Inc. · 2003
- Chromatographic resins and methods for using same57US 5,652,348 AMassey University · 1997
- Retentate chromatography and protein chip arrays with applications in biology and medicine44US 6,844,165 B2Ciphergen Biosystems, Inc. · 2005