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US 2026/0133202 A1Published application
QUANTITATIVE DETERMINATION METHOD FOR Hex4, LYSO-GM1, Fuc-GlcNAc-Asn, AND LYSO-SULFATIDE INCLUDED IN CEREBROSPINAL FLUID
AssigneeJCR Pharmaceuticals Co., Ltd.
InventorsHidehiko HASHIMOTO, Satowa TANAKA, Tomoki FUKATSU, Noboru TANAKA
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Abstract
A method for quantifying Hex4, lyso-GM1, Fuc-GlcNAc-Asn, or lyso-sulfatide included in cerebrospinal fluid, the method including adding an internal standard substance to a solution including the cerebrospinal fluid, submitting the solution including the cerebrospinal fluid, to which the internal standard substance has been added, to liquid chromatography to obtain an eluate, and subjecting the eluate to mass analysis.
Claims9
A method for quantifying Hex4 in cerebrospinal fluid, comprising:
- adding an internal standard substance to a solution comprising cerebrospinal fluid;
- applying the solution comprising the cerebrospinal fluid and the internal standard substance to liquid chromatography to obtain an eluate;
- and
- subjecting the eluate to mass analysis to quantify the Hex4 in the cerebrospinal fluid.
1 more element
(canceled)
9-29. (canceled)
Dependencies are inferred from the claim text.