A61K 39/0225
Spirochetes
Official title: {Spirochetes, e.g. Treponema, Leptospira, Borrelia}
A61K39/0225 (Spirochetes) appears on 186 US grants and 230 published applications in this corpus.
Search patents in A61K- Granted patents
- 186
- Published applications
- 230
- Assignees
- 147
- Inventors
- 424
- Latest grant
- 7 Apr 2026
Filings by year
| Year | Granted patents | Published applications |
|---|---|---|
| 1978 | 2 | 0 |
| 1979 | 4 | 0 |
| 1980 | 1 | 0 |
| 1981 | 0 | 0 |
| 1982 | 0 | 0 |
| 1983 | 0 | 0 |
| 1984 | 2 | 0 |
| 1985 | 1 | 0 |
| 1986 | 1 | 0 |
| 1987 | 0 | 0 |
| 1988 | 4 | 0 |
| 1989 | 0 | 0 |
| 1990 | 0 | 0 |
| 1991 | 1 | 0 |
| 1992 | 1 | 0 |
| 1993 | 1 | 0 |
| 1994 | 1 | 0 |
| 1995 | 1 | 0 |
| 1996 | 2 | 0 |
| 1997 | 3 | 0 |
| 1998 | 5 | 0 |
| 1999 | 2 | 0 |
| 2000 | 3 | 0 |
| 2001 | 6 | 1 |
| 2002 | 2 | 3 |
| 2003 | 5 | 2 |
| 2004 | 0 | 8 |
| 2005 | 1 | 7 |
| 2006 | 10 | 10 |
| 2007 | 3 | 5 |
| 2008 | 1 | 7 |
| 2009 | 3 | 8 |
| 2010 | 3 | 7 |
| 2011 | 1 | 12 |
| 2012 | 4 | 8 |
| 2013 | 3 | 7 |
| 2014 | 12 | 13 |
| 2015 | 8 | 17 |
| 2016 | 13 | 13 |
| 2017 | 8 | 12 |
| 2018 | 14 | 12 |
| 2019 | 8 | 8 |
| 2020 | 11 | 13 |
| 2021 | 7 | 8 |
| 2022 | 7 | 6 |
| 2023 | 5 | 10 |
| 2024 | 7 | 11 |
| 2025 | 7 | 14 |
| 2026 | 2 | 8 |
By publication year. Applications have been published since 2001. 2026 runs to 8 Oct.
Recent patents
- Leptospiral proteins and uses thereof7 Apr 2026US 12,595,287 B2Yale University
- Compositions comprising three OspA fusion proteins for medical use6 Jan 2026US 12,514,912 B2Pfizer Inc.
- Modified HIV-1 proviral vectors with enhanced dendritic cell transduction efficiencies comprising the JRFL envelope23 Dec 2025US 12,503,499 B2University of Massachusetts
- Methods and compositions for the diagnosis, prophylaxis and treatment of Lyme disease22 Jul 2025US 12,364,744 B2Lankenau Institute for Medical Research
- Multivalent OspA polypeptides and methods and uses relating thereto17 Jun 2025US 12,331,084 B2Valneva Austria GmbH
- Compositions comprising three ospa fusion proteins for medical use1 Oct 2026US 2026/0295025 A1Pfizer Inc.
- Tp0751 chimera-containing vaccine1 Oct 2026US 2026/0297141 A1University of Washington
- Vaccine for protection against leptospira serovar australis9 Jul 2026US 2026/0191941 A1Intervet Inc.
- Use of modified hiv-1 for generating fully human antibodies2 Jul 2026US 2026/0184767 A1University of Massachusetts
- Mutant fragments of ospa and methods and uses relating thereto12 Mar 2026US 2026/0070950 A1Valneva Austria GmbH
Most cited
By later US patents
- Compositions and methods for delivery of genetic material184US 5,739,118 AApollon Inc. · 1998
- Antigen library immunization76US 6,541,011 B2Maxygen, Inc. · 2003
- Vaccine against lyme disease41US 4,721,617 ARegents of the University of Minnesota · 1988
- Microfluidized oil-in-water emulsions and vaccine compositions41US 7,122,191 B2Pfizer Inc. · 2006
- Method of increasing the effectiveness of oral vaccination for swine dysentery27US 4,152,415 AChromalloy American Corporation · 1979