A61K 38/005
Enzyme inhibitors
Official title: {Enzyme inhibitors (protease inhibitors A61K38/55)}
A61K38/005 (Enzyme inhibitors) appears on 455 US grants and 732 published applications in this corpus.
Search patents in A61K- Granted patents
- 455
- Published applications
- 732
- Assignees
- 398
- Inventors
- 1,381
- Latest grant
- 8 Sep 2026
Filings by year
| Year | Granted patents | Published applications |
|---|---|---|
| 1976 | 1 | 0 |
| 1977 | 1 | 0 |
| 1978 | 1 | 0 |
| 1979 | 0 | 0 |
| 1980 | 1 | 0 |
| 1981 | 3 | 0 |
| 1982 | 3 | 0 |
| 1983 | 2 | 0 |
| 1984 | 2 | 0 |
| 1985 | 1 | 0 |
| 1986 | 1 | 0 |
| 1987 | 4 | 0 |
| 1988 | 2 | 0 |
| 1989 | 4 | 0 |
| 1990 | 3 | 0 |
| 1991 | 4 | 0 |
| 1992 | 4 | 0 |
| 1993 | 4 | 0 |
| 1994 | 4 | 0 |
| 1995 | 5 | 0 |
| 1996 | 4 | 0 |
| 1997 | 2 | 0 |
| 1998 | 2 | 0 |
| 1999 | 6 | 0 |
| 2000 | 3 | 0 |
| 2001 | 5 | 0 |
| 2002 | 6 | 5 |
| 2003 | 5 | 9 |
| 2004 | 4 | 14 |
| 2005 | 2 | 23 |
| 2006 | 5 | 12 |
| 2007 | 6 | 14 |
| 2008 | 7 | 17 |
| 2009 | 6 | 19 |
| 2010 | 7 | 12 |
| 2011 | 8 | 18 |
| 2012 | 10 | 19 |
| 2013 | 13 | 33 |
| 2014 | 18 | 48 |
| 2015 | 18 | 51 |
| 2016 | 28 | 59 |
| 2017 | 27 | 42 |
| 2018 | 31 | 54 |
| 2019 | 30 | 56 |
| 2020 | 31 | 51 |
| 2021 | 31 | 40 |
| 2022 | 26 | 51 |
| 2023 | 23 | 30 |
| 2024 | 23 | 25 |
| 2025 | 13 | 18 |
| 2026 | 5 | 12 |
By publication year. Applications have been published since 2001. 2026 runs to 8 Oct.
Recent patents
- Combination pharmaceutical of temozolomide and mutant IDHI enzyme inhibitor8 Sep 2026US 12,728,150 B2Daiichi Sankyo Company, Limited
- Methods of treatment14 Apr 2026US 12,599,603 B2Intra-Cellular Therapies, Inc.
- Methods and compositions for treatment of pancreatic cancer7 Apr 2026US 12,594,324 B2
- Compositions and methods to treat metastatic gastrointestinal cancer24 Mar 2026US 12,582,667 B2The Rockefeller University
- Methods and compositions for inhibiting glyoxalase 1 (GLO1)13 Jan 2026US 12,521,426 B2
- Reducing systemic regulatory t cell levels or activity for treatment of disease and injury of the cns1 Oct 2026US 2026/0297191 A1ImmunoBrain Checkpoint, Inc.
- Implantable Ocular Device And Method of Corneal Treatment17 Sep 2026US 2026/0272709 A1
- Lisinopril formulations10 Sep 2026US 2026/0263549 A1Azurity Pharmaceuticals, Inc.
- Pic1 inhibition of myeloperoxidase oxidative activity in an animal model10 Sep 2026US 2026/0263566 A1Realta Holdings, LLC
- Skin composition3 Sep 2026US 2026/0256870 A1Eaderm Co., Ltd.
Most cited
By later US patents
- Fibrinogen-containing dry preparation, manufacture and use thereof225US 4,442,655 ASerapharm Michael Stroetmann · 1984
- Tissue adhesive201US 4,362,567 AImmuno Aktiengesellschaft fur chemisch-medizinische Produkte · 1982
- Enriched plasma derivative for advancement of wound closure and healing186US 4,427,650 ASerapharm Michael Stroetmann · 1984
- Tissue adhesive161US 4,414,976 AImmuno Aktiengesellschaft fur chemischmedizinische Produkte · 1983
- Blood coagulation factors and process for their manufacture135US 4,297,344 ABehringwerke Aktiengesellschaft · 1981