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US 2026/0256870 A1Published application
Skin composition
AssigneeEaderm Co., Ltd.
InventorEmi Nishimura
Life of this patent
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AssigneeEaderm Co., Ltd.
InventorEmi Nishimura
Estimating the term…
A method and composition for promoting skin wound healing; for preventing or ameliorating ulcers and bedsores; for preventing skin aging; for preventing or ameliorating skin damage caused by an anticancer agent; and for enhancing the regeneration ability of epidermal stem cells. The composition includes, as an active ingredient, a substance which induces or maintains the expression of COL17A1 in cells, a substance which inhibits the degradation of COL17A1 in cells, a substance which promotes the competitive amplification ability of epidermal stem cells, a substance which suppresses genomic stress or oxidative stress in cells and or a substance which prevents DNA damage in cells, enables the promotion of skin wound healing, protection from an anticancer agent and prevention of skin aging. The composition enhances the regeneration ability of epidermal stem cells.
A method for promoting skin wound healing, or preventing or improving skin ulcers or decubitus ulcers, comprising administering to a subject in need thereof a composition comprising as an active ingredient a substance selected from the group consisting of a substance that induces or maintains the expression of COL17A1 in a cell, a substance that inhibits the degradation of COL17A1 in a cell, a substance that maintains the self-renewal ability of epidermal stem cells, a substance that inhibits genomic stress in a cell, and a substance that inhibits DNA damage in a cell.
Dependencies are inferred from the claim text.