A61K 31/405
Indole-alkanecarboxylic acids
Official title: Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin
A61K31/405 (Indole-alkanecarboxylic acids) appears on 1,794 US grants and 2,852 published applications in this corpus.
Search patents in A61K- Granted patents
- 1,794
- Published applications
- 2,852
- Assignees
- 1,274
- Inventors
- 5,010
- Latest grant
- 22 Sep 2026
Filings by year
| Year | Granted patents | Published applications |
|---|---|---|
| 1976 | 4 | 0 |
| 1977 | 4 | 0 |
| 1978 | 6 | 0 |
| 1979 | 10 | 0 |
| 1980 | 12 | 0 |
| 1981 | 5 | 0 |
| 1982 | 6 | 0 |
| 1983 | 5 | 0 |
| 1984 | 7 | 0 |
| 1985 | 4 | 0 |
| 1986 | 2 | 0 |
| 1987 | 9 | 0 |
| 1988 | 11 | 0 |
| 1989 | 7 | 0 |
| 1990 | 15 | 0 |
| 1991 | 12 | 0 |
| 1992 | 11 | 0 |
| 1993 | 19 | 0 |
| 1994 | 11 | 0 |
| 1995 | 15 | 0 |
| 1996 | 36 | 0 |
| 1997 | 64 | 0 |
| 1998 | 40 | 0 |
| 1999 | 53 | 0 |
| 2000 | 41 | 0 |
| 2001 | 40 | 16 |
| 2002 | 51 | 61 |
| 2003 | 34 | 119 |
| 2004 | 49 | 147 |
| 2005 | 27 | 109 |
| 2006 | 72 | 142 |
| 2007 | 39 | 126 |
| 2008 | 37 | 88 |
| 2009 | 35 | 100 |
| 2010 | 36 | 96 |
| 2011 | 41 | 84 |
| 2012 | 31 | 88 |
| 2013 | 50 | 116 |
| 2014 | 63 | 142 |
| 2015 | 71 | 141 |
| 2016 | 81 | 135 |
| 2017 | 73 | 129 |
| 2018 | 65 | 118 |
| 2019 | 65 | 107 |
| 2020 | 79 | 105 |
| 2021 | 56 | 124 |
| 2022 | 72 | 127 |
| 2023 | 77 | 132 |
| 2024 | 50 | 108 |
| 2025 | 55 | 92 |
| 2026 | 36 | 100 |
By publication year. Applications have been published since 2001. 2026 runs to 8 Oct.
Recent patents
- Compositions and methods using at least one glycine or derivative thereof and at least one large neutral amino acid and/or cationic amino acid or precursor thereof22 Sep 2026US 12,740,958 B2Societe des Produits Nestle S. A.
- Orthodontic devices for delivery of an active agent8 Sep 2026US 12,727,970 B2Smylio Inc.
- Alpha-methyl-L-tryptophan as an orally active drug for treating or preventing metabolic conditions1 Sep 2026US 12,721,836 B2Texas Tech University System
- Combination cancer therapy using CHK inhibitor25 Aug 2026US 12,714,707 B2Shanghai Huayu Biotechnology Co. Ltd
- Crystalline forms of solvates of tryptophan derivatives, compositions comprising them and uses thereof11 Aug 2026US 12,703,685 B2Galimedix Therapeutics, Inc.
- Composition for removing and inhibiting senescent cells, and uses thereof8 Oct 2026US 2026/0306460 A1Lifeceutix Co., Ltd.
- Novel 3d printing concept for pharmaceutical dosage forms via selective laser sintering1 Oct 2026US 2026/0294742 A1Merck Patent GmbH
- Methods for treating gastrointestinal inflammatory diseases using alpha-ketoglutarate (akg) modulators1 Oct 2026US 2026/0294856 A1
- Indole lactate for the treatment of multiple sclerosis1 Oct 2026US 2026/0294870 A1The Johns Hopkins University
- Amino acid-derived ceramide, synthesis method therefor and use thereof1 Oct 2026US 2026/0297018 A1Shenzhen Dikeman Biotechnology Co., Ltd.
Most cited
By later US patents
- Amphoteric compositions and polymeric forms of alpha hydroxyacids, and their therapeutic use354US 5,091,171 A1992
- Method for treating infectious respiratory diseases270US 5,290,540 AThe Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. · 1994
- Long-term sustained-release preparation174US 4,774,091 ASumitomo Pharmaceuticals Company, Limited · 1988
- Recombinant A2-specific TNFα specific antibodies174US 7,070,775 B2Centocor, Inc. · 2006
- Selected essential amino acid supplementation of dietary proteins to lower urinary urea and peak glucose levels164US 6,602,909 B12003