A61K 31/40
Having five-membered rings with one nitrogen as the only ring hetero atom
Official title: having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
A61K31/40 (Having five-membered rings with one nitrogen as the only ring hetero atom) appears on 12,444 US grants and 21,131 published applications in this corpus.
Search patents in A61K- Granted patents
- 12,444
- Published applications
- 21,131
- Assignees
- 6,391
- Inventors
- 36,173
- Latest grant
- 6 Oct 2026
Filings by year
| Year | Granted patents | Published applications |
|---|---|---|
| 1976 | 18 | 0 |
| 1977 | 11 | 0 |
| 1978 | 19 | 0 |
| 1979 | 21 | 0 |
| 1980 | 31 | 0 |
| 1981 | 13 | 0 |
| 1982 | 14 | 0 |
| 1983 | 16 | 0 |
| 1984 | 16 | 0 |
| 1985 | 20 | 0 |
| 1986 | 23 | 0 |
| 1987 | 34 | 0 |
| 1988 | 44 | 0 |
| 1989 | 55 | 0 |
| 1990 | 64 | 0 |
| 1991 | 78 | 0 |
| 1992 | 82 | 0 |
| 1993 | 89 | 0 |
| 1994 | 68 | 0 |
| 1995 | 120 | 0 |
| 1996 | 179 | 0 |
| 1997 | 238 | 0 |
| 1998 | 211 | 0 |
| 1999 | 227 | 0 |
| 2000 | 238 | 0 |
| 2001 | 224 | 112 |
| 2002 | 268 | 402 |
| 2003 | 223 | 555 |
| 2004 | 171 | 668 |
| 2005 | 161 | 642 |
| 2006 | 249 | 604 |
| 2007 | 180 | 616 |
| 2008 | 159 | 595 |
| 2009 | 168 | 593 |
| 2010 | 231 | 647 |
| 2011 | 238 | 675 |
| 2012 | 272 | 687 |
| 2013 | 409 | 840 |
| 2014 | 535 | 1035 |
| 2015 | 601 | 1026 |
| 2016 | 647 | 1070 |
| 2017 | 667 | 1064 |
| 2018 | 673 | 1013 |
| 2019 | 708 | 1022 |
| 2020 | 665 | 1051 |
| 2021 | 636 | 1091 |
| 2022 | 573 | 1124 |
| 2023 | 513 | 1112 |
| 2024 | 525 | 1074 |
| 2025 | 480 | 1032 |
| 2026 | 339 | 781 |
By publication year. Applications have been published since 2001. 2026 runs to 8 Oct.
Subgroups
Granted patents
- A61K 31/403Condensed with carbocyclic rings6,082
- A61K 31/407Condensed with other heterocyclic ring systems1,647
- A61K 31/4025Not condensed and containing further heterocyclic rings1,217
- A61K 31/4015Having oxo groups directly attached to the heterocyclic ring814
- A61K 31/401Proline737
- A61K 31/409Having four such rings290
- A61K 31/4021-aryl substituted242
Recent patents
- Method and apparatus for delivering an API-containing liquid to an edible substrate6 Oct 2026US 12,751,915 B2Transport Authority, Inc.
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- Methods for delivery of psychedelic medications by inhalation and systems for performing the methods6 Oct 2026US 12,751,940 B2Cybin IRL Limited
- Combination drug for the control and management of type 2 diabetes mellitus6 Oct 2026US 12,751,958 B2Laboratorios Silanes S.A. de C.V.
- Small molecule inhibitors of viral replication6 Oct 2026US 12,751,963 B2The Trustees of Princeton University
- Use of small molecules to increase hypoxia inducible factor (hif) activity8 Oct 2026US 2026/0306440 A1Brown University
- Method and pharmaceutical composition for treating a sleep disorder8 Oct 2026US 2026/0306442 A1Overseas Pharmaceuticals, Ltd.
- Combination treatment for netherton syndrome8 Oct 2026US 2026/0306448 A1Quoin Pharmaceuticals, Inc.
- Crystal form of lipoprotein compound and preparation method therefor8 Oct 2026US 2026/0306449 A1Jiangsu Hengrui Pharmaceuticals Co., Ltd.
- Combination treatment with cisplatin and pg3 for p53-mutated head and neck cancers8 Oct 2026US 2026/0306450 A1Brown University
Most cited
By later US patents
- Method of treating androgen independent prostate cancer1,091US 9,040,574 B2Natrogen Therapeutics International, Inc. · 2015
- Method for manufacturing a porous ceramic scaffold having an organic/inorganic hybrid coating layer containing a bioactive factor777US 8,734,831 B2Snu R&Db Foundation · 2014
- Methods for treating multiple myeloma with 3-(4-amino-1-oxo-1,3-dihydro-isoindol-2-yl)-piperidine-2,6-dione after stem cell transplantation733US 9,101,621 B2Celgene Corporation · 2015
- Liquid reservoir transdermal patch for the administration of ketorolac673US 5,591,767 APharmetrix Corporation · 1997
- Therapeutic inhibitor of vascular smooth muscle cells562US 5,733,925 ANeoRx Corporation · 1998