A61K 31/4025
Not condensed and containing further heterocyclic rings
Official title: not condensed and containing further heterocyclic rings, e.g. cromakalim
A61K31/4025 (Not condensed and containing further heterocyclic rings) appears on 1,217 US grants and 1,898 published applications in this corpus.
Search patents in A61K- Granted patents
- 1,217
- Published applications
- 1,898
- Assignees
- 891
- Inventors
- 4,424
- Latest grant
- 6 Oct 2026
Filings by year
| Year | Granted patents | Published applications |
|---|---|---|
| 1976 | 1 | 0 |
| 1977 | 0 | 0 |
| 1978 | 0 | 0 |
| 1979 | 0 | 0 |
| 1980 | 0 | 0 |
| 1981 | 0 | 0 |
| 1982 | 0 | 0 |
| 1983 | 0 | 0 |
| 1984 | 0 | 0 |
| 1985 | 0 | 0 |
| 1986 | 0 | 0 |
| 1987 | 0 | 0 |
| 1988 | 2 | 0 |
| 1989 | 0 | 0 |
| 1990 | 3 | 0 |
| 1991 | 0 | 0 |
| 1992 | 1 | 0 |
| 1993 | 1 | 0 |
| 1994 | 0 | 0 |
| 1995 | 14 | 0 |
| 1996 | 32 | 0 |
| 1997 | 25 | 0 |
| 1998 | 29 | 0 |
| 1999 | 31 | 0 |
| 2000 | 31 | 0 |
| 2001 | 31 | 9 |
| 2002 | 23 | 29 |
| 2003 | 25 | 46 |
| 2004 | 11 | 35 |
| 2005 | 5 | 26 |
| 2006 | 25 | 45 |
| 2007 | 8 | 35 |
| 2008 | 14 | 40 |
| 2009 | 13 | 37 |
| 2010 | 19 | 64 |
| 2011 | 27 | 71 |
| 2012 | 43 | 85 |
| 2013 | 49 | 97 |
| 2014 | 72 | 114 |
| 2015 | 79 | 130 |
| 2016 | 83 | 114 |
| 2017 | 85 | 106 |
| 2018 | 56 | 81 |
| 2019 | 74 | 104 |
| 2020 | 50 | 99 |
| 2021 | 58 | 86 |
| 2022 | 52 | 84 |
| 2023 | 32 | 76 |
| 2024 | 39 | 88 |
| 2025 | 37 | 106 |
| 2026 | 37 | 91 |
By publication year. Applications have been published since 2001. 2026 runs to 8 Oct.
Recent patents
- Topical ocular delivery of cromakalim6 Oct 2026US 12,751,939 B2Mayo Foundtation for Medical Education and Research
- Compounds for treating CNS- and neurodegenerative diseases29 Sep 2026US 12,746,224 B2ETH Zurich
- Compositions and methods comprising endothelin a receptor antagonists and androgen therapies29 Sep 2026US 12,746,239 B2The United States Government as represented by the Department of Veterans Affairs
- TEAD inhibitors29 Sep 2026US 12,747,207 B2Orion Corporation
- Pharmaceutical compounds and methods of making and using the same29 Sep 2026US 12,747,208 B2Athos Therapeutics, Inc.
- Use of small molecules to increase hypoxia inducible factor (hif) activity8 Oct 2026US 2026/0306440 A1Brown University
- Crystal form of lipoprotein compound and preparation method therefor8 Oct 2026US 2026/0306449 A1Jiangsu Hengrui Pharmaceuticals Co., Ltd.
- Combination treatment with cisplatin and pg3 for p53-mutated head and neck cancers8 Oct 2026US 2026/0306450 A1Brown University
- Combination therapy for pulmonary hypertension8 Oct 2026US 2026/0306461 A1Vivus, Inc.
- Inhaled statins as bronchodilators to improve lung function in respiratory diseases8 Oct 2026US 2026/0306477 A1Beth Israel Deaconess Medical Center, Inc.
Most cited
By later US patents
- Method for manufacturing a porous ceramic scaffold having an organic/inorganic hybrid coating layer containing a bioactive factor777US 8,734,831 B2Snu R&Db Foundation · 2014
- Therapeutic inhibitor of vascular smooth muscle cells562US 5,733,925 ANeoRx Corporation · 1998
- Therapeutic inhibitor of vascular smooth muscle cells438US 5,981,568 ANeoRx Corporation · 1999
- Therapeutic inhibitor of vascular smooth muscle cells308US 6,074,659 ANoeRx Corporation · 2000
- Therapeutic inhibitor of vascular smooth muscle cells280US 5,811,447 ANeoRx Corporation · 1998