Combination treatment with cisplatin and pg3 for p53-mutated head and neck cancers
AssigneeBrown University
InventorsWafik El-Deiry, Xiaobing Tian
Life of this patent
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Abstract
A method of treating cancer in a subject, comprising administering to the subject a therapeutically effective amount of a composition comprising a combination of cisplatin or a cisplatin derivative and PG3, is described. A method of preventing cisplatin resistance and cancer recurrence in a subject, comprising administering to the subject a prophylactically effective amount of a composition comprising a combination of cisplatin or a cisplatin derivative and PG3, is also described. Pharmaceutical compositions comprising cisplatin or a cisplatin derivative and PG3 are also described.
Claims20
A method of treating cancer in a subject, comprising administering to the subject a therapeutically effective amount of a pharmaceutical composition comprising a combination of cisplatin or a cisplatin derivative and PG3 or a pharmaceutically acceptable salt thereof.
A method of preventing cisplatin resistance and cancer recurrence in a subject, comprising administering to the subject a prophylactically effective amount of a pharmaceutical composition comprising a combination of cisplatin or a cisplatin derivative and PG3.
Dependencies are inferred from the claim text.