A61K 31/401
Proline
Official title: Proline; Derivatives thereof, e.g. captopril
A61K31/401 (Proline) appears on 737 US grants and 1,572 published applications in this corpus.
Search patents in A61K- Granted patents
- 737
- Published applications
- 1,572
- Assignees
- 654
- Inventors
- 2,606
- Latest grant
- 29 Sep 2026
Filings by year
| Year | Granted patents | Published applications |
|---|---|---|
| 1991 | 1 | 0 |
| 1992 | 4 | 0 |
| 1993 | 2 | 0 |
| 1994 | 0 | 0 |
| 1995 | 1 | 0 |
| 1996 | 5 | 0 |
| 1997 | 5 | 0 |
| 1998 | 3 | 0 |
| 1999 | 10 | 0 |
| 2000 | 16 | 0 |
| 2001 | 29 | 10 |
| 2002 | 17 | 47 |
| 2003 | 13 | 52 |
| 2004 | 12 | 89 |
| 2005 | 10 | 105 |
| 2006 | 18 | 88 |
| 2007 | 19 | 101 |
| 2008 | 16 | 54 |
| 2009 | 10 | 58 |
| 2010 | 25 | 58 |
| 2011 | 25 | 41 |
| 2012 | 22 | 37 |
| 2013 | 29 | 47 |
| 2014 | 36 | 66 |
| 2015 | 34 | 59 |
| 2016 | 29 | 62 |
| 2017 | 40 | 68 |
| 2018 | 37 | 62 |
| 2019 | 41 | 53 |
| 2020 | 37 | 67 |
| 2021 | 40 | 62 |
| 2022 | 35 | 69 |
| 2023 | 41 | 36 |
| 2024 | 25 | 56 |
| 2025 | 29 | 43 |
| 2026 | 21 | 82 |
By publication year. Applications have been published since 2001. 2026 runs to 8 Oct.
Recent patents
- Pharmaceutical compounds and methods of making and using the same29 Sep 2026US 12,747,208 B2Athos Therapeutics, Inc.
- Amino acid compositions22 Sep 2026US 12,741,941 B2ThermoLife International, LLC
- Plant essential oil amino acid composition and preparation method therefor1 Sep 2026US 12,721,821 B2Cocrystal Technology (Jiaxing) Co., Ltd.
- Combination treatment for Netherton syndrome1 Sep 2026US 12,721,834 B2Quoin Pharmaceuticals, Inc.
- Formulations and methods for treating diarrhea25 Aug 2026US 12,714,687 B2
- Combination treatment for netherton syndrome8 Oct 2026US 2026/0306448 A1Quoin Pharmaceuticals, Inc.
- Amino acid-derived ceramide, synthesis method therefor and use thereof1 Oct 2026US 2026/0297018 A1Shenzhen Dikeman Biotechnology Co., Ltd.
- Oral formulations of pyrrolidine derivatives24 Sep 2026US 2026/0284006 A1ReproNovo SA
- Trpv1 agonist and uses thereof17 Sep 2026US 2026/0274802 A1SciTherm Therapeutics Corporation
- Lisinopril formulations10 Sep 2026US 2026/0263549 A1Azurity Pharmaceuticals, Inc.
Most cited
By later US patents
- Use of dipeptidyl peptidase IV effectors for lowering the blood glucose level in mammals233US 6,303,661 B1Probiodrug AG · 2001
- Pharmaceutical composition containing acid addition salt of basic drug163US 6,255,502 B1Farmarc Nederland BV · 2001
- Captopril formulation providing increased duration of activity125US 5,158,777 AE. R. Squibb & Sons, Inc. · 1992
- Method of producing multi-layer medicaments in solid form for oral or rectal administration124US 6,120,802 ABASF SE · 2000
- Treatment of female fertility conditions through modulation of the autonomic nervous system122US 7,676,269 B2Palo Alto Investors · 2010