A61K 31/155
Amidines
Official title: Amidines ([IMAGE cpc-sch-A61K-1029.gif]), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
A61K31/155 (Amidines) appears on 1,944 US grants and 3,438 published applications in this corpus.
Search patents in A61K- Granted patents
- 1,944
- Published applications
- 3,438
- Assignees
- 1,479
- Inventors
- 5,752
- Latest grant
- 6 Oct 2026
Filings by year
| Year | Granted patents | Published applications |
|---|---|---|
| 1976 | 13 | 0 |
| 1977 | 17 | 0 |
| 1978 | 6 | 0 |
| 1979 | 1 | 0 |
| 1980 | 5 | 0 |
| 1981 | 5 | 0 |
| 1982 | 4 | 0 |
| 1983 | 4 | 0 |
| 1984 | 1 | 0 |
| 1985 | 5 | 0 |
| 1986 | 3 | 0 |
| 1987 | 1 | 0 |
| 1988 | 3 | 0 |
| 1989 | 4 | 0 |
| 1990 | 7 | 0 |
| 1991 | 6 | 0 |
| 1992 | 15 | 0 |
| 1993 | 23 | 0 |
| 1994 | 23 | 0 |
| 1995 | 13 | 0 |
| 1996 | 15 | 0 |
| 1997 | 23 | 0 |
| 1998 | 32 | 0 |
| 1999 | 35 | 0 |
| 2000 | 28 | 0 |
| 2001 | 33 | 12 |
| 2002 | 36 | 35 |
| 2003 | 25 | 63 |
| 2004 | 19 | 74 |
| 2005 | 19 | 93 |
| 2006 | 18 | 70 |
| 2007 | 20 | 98 |
| 2008 | 10 | 67 |
| 2009 | 11 | 78 |
| 2010 | 25 | 95 |
| 2011 | 33 | 130 |
| 2012 | 60 | 146 |
| 2013 | 74 | 140 |
| 2014 | 91 | 174 |
| 2015 | 88 | 190 |
| 2016 | 99 | 199 |
| 2017 | 129 | 210 |
| 2018 | 123 | 196 |
| 2019 | 125 | 173 |
| 2020 | 104 | 206 |
| 2021 | 111 | 234 |
| 2022 | 84 | 211 |
| 2023 | 83 | 158 |
| 2024 | 91 | 176 |
| 2025 | 84 | 111 |
| 2026 | 57 | 99 |
By publication year. Applications have been published since 2001. 2026 runs to 8 Oct.
Recent patents
- Combination drug for the control and management of type 2 diabetes mellitus6 Oct 2026US 12,751,958 B2Laboratorios Silanes S.A. de C.V.
- Synergistic activity of novel compounds against planktonic and biofilm cells of clinically relevant pathogens6 Oct 2026US 12,752,038 B2SterileCare Inc.
- Short conjugated oligoelectrolytesand antibiotics22 Sep 2026US 12,740,950 B2Nanyang Technological University
- Probiotics for regulating blood glucose15 Sep 2026US 12,734,200 B2Genbioma Aplicaciones, S.L.
- Compounds for the treatment of bacterial infections and potentiation of antibiotics8 Sep 2026US 12,728,105 B2Georgia State University Research Foundation, Inc.
- Methods of preventing post-traumatic osteoarthritis using metformin8 Oct 2026US 2026/0306428 A1
- Method of inhibiting adenosine triphosphate secretion, method of inhibiting hepatic stellate cell activation, method of deactivating hepatic stellate cell, method of treating hepatic fibrosis, method of treating non-alcoholic steatohepatitis, and method of treating psoriasis8 Oct 2026US 2026/0306500 A1Kurume University
- Microrna as a diagnostic tool and for developing advanced therapies of amyotrophic lateral sclerosis (als) with bulbar onset8 Oct 2026US 2026/0308682 A1Consiglio Nazionale Delle Ricerche
- Compositions and methods using thymol and/or carvacrol for induction of autophagy1 Oct 2026US 2026/0294840 A1Societe des Produits Nestle S. A.
- Method for treating and preventing covid-191 Oct 2026US 2026/0294902 A1University of South Florida
Most cited
By later US patents
- Methods and devices for treating plumonary vasoconstriction and asthma251US 5,485,827 AThe General Hospital Corporation · 1996
- Albumin fusion proteins comprising GLP-1 polypeptides198US 7,141,547 B2Human Genome Sciences, Inc. · 2006
- Vascular treatment method and apparatus179US 5,900,433 ACormedics Corp. · 1999
- Dosage form for high dose-high solubility active ingredients that provides for immediate release and modified release of the active ingredients174US 8,263,125 B2Torrent Pharmaceuticals Limited · 2012
- Methods and devices for treating pulmonary vasoconstriction and asthma158US 5,873,359 AThe General Hospital Corporation · 1999