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US 2026/0306500 A1Published application
Method of inhibiting adenosine triphosphate secretion, method of inhibiting hepatic stellate cell activation, method of deactivating hepatic stellate cell, method of treating hepatic fibrosis, method of treating non-alcoholic steatohepatitis, and method of treating psoriasis
AssigneeKurume University
InventorsMasatoshi NOMURA, Yoshinori MORIYAMA, Nao HASUZAWA, Sawako MORIYAMA
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Abstract
An adenosine triphosphate secretion inhibitor includes: imeglimin, metformin, phosphoenolpyruvic acid, an analog of phosphoenolpyruvic acid, or a pharmaceutically acceptable salt thereof.
Claims9
A method of inhibiting adenosine triphosphate secretion, comprising:
- administrating, to a subject, imeglimin, metformin, phosphoenolpyruvic acid, an analog of phosphoenolpyruvic acid, or a pharmaceutically acceptable salt thereof.
A method of inhibiting hepatic stellate cell activation, comprising:
- administrating, to a subject, imeglimin, metformin, phosphoenolpyruvic acid, an analog of phosphoenolpyruvic acid, or a pharmaceutically acceptable salt thereof.
A method of deactivating hepatic stellate cell, comprising:
- administrating, to a subject, imeglimin, metformin, phosphoenolpyruvic acid, an analog of phosphoenolpyruvic acid, or a pharmaceutically acceptable salt thereof.
A method of treating hepatic fibrosis, comprising:
- administrating, to a subject, imeglimin, metformin, phosphoenolpyruvic acid, an analog of phosphoenolpyruvic acid, or a pharmaceutically acceptable salt thereof.
A method of treating non-alcoholic steatohepatitis, comprising:
- administrating, to a subject, imeglimin, metformin, phosphoenolpyruvic acid, an analog of phosphoenolpyruvic acid, or a pharmaceutically acceptable salt thereof.
A method of treating psoriasis, comprising:
- administrating, to a subject, imeglimin, metformin, phosphoenolpyruvic acid, an analog of phosphoenolpyruvic acid, or a pharmaceutically acceptable salt thereof.
(canceled)
Dependencies are inferred from the claim text.