C12Y 301/00
Hydrolases acting on ester bonds
Official title: Hydrolases acting on ester bonds (3.1)
C12Y301/00 (Hydrolases acting on ester bonds) appears on 3,364 US grants and 6,014 published applications in this corpus.
Search patents in C12Y- Granted patents
- 3,364
- Published applications
- 6,014
- Assignees
- 1,968
- Inventors
- 10,138
- Latest grant
- 6 Oct 2026
Filings by year
| Year | Granted patents | Published applications |
|---|---|---|
| 1983 | 1 | 0 |
| 1984 | 1 | 0 |
| 1985 | 1 | 0 |
| 1986 | 1 | 0 |
| 1987 | 3 | 0 |
| 1988 | 7 | 0 |
| 1989 | 4 | 0 |
| 1990 | 7 | 0 |
| 1991 | 5 | 0 |
| 1992 | 4 | 0 |
| 1993 | 5 | 0 |
| 1994 | 7 | 0 |
| 1995 | 12 | 0 |
| 1996 | 12 | 0 |
| 1997 | 17 | 0 |
| 1998 | 16 | 0 |
| 1999 | 28 | 0 |
| 2000 | 28 | 0 |
| 2001 | 37 | 5 |
| 2002 | 38 | 58 |
| 2003 | 32 | 102 |
| 2004 | 31 | 94 |
| 2005 | 26 | 111 |
| 2006 | 33 | 75 |
| 2007 | 18 | 74 |
| 2008 | 31 | 66 |
| 2009 | 26 | 97 |
| 2010 | 40 | 111 |
| 2011 | 54 | 118 |
| 2012 | 66 | 156 |
| 2013 | 106 | 182 |
| 2014 | 120 | 248 |
| 2015 | 135 | 331 |
| 2016 | 192 | 415 |
| 2017 | 192 | 417 |
| 2018 | 233 | 330 |
| 2019 | 266 | 421 |
| 2020 | 290 | 378 |
| 2021 | 252 | 409 |
| 2022 | 230 | 378 |
| 2023 | 183 | 352 |
| 2024 | 243 | 408 |
| 2025 | 202 | 373 |
| 2026 | 129 | 305 |
By publication year. Applications have been published since 2001. 2026 runs to 8 Oct.
Subgroups
Granted patents
- C12Y 301/01Carboxylic ester hydrolases1,014
- C12Y 301/03Phosphoric monoester hydrolases788
- C12Y 301/21Endodeoxyribonucleases producing 5'-phosphomonoesters349
- C12Y 301/04Phosphoric diester hydrolases297
- C12Y 301/02Thioester hydrolases246
- C12Y 301/06Sulfuric ester hydrolases152
- C12Y 301/27Endoribonucleases producing 3'-phosphomonoesters126
- C12Y 301/26Endoribonucleases producing 5'-phosphomonoesters67
All 20 subgroupsShow fewer
- C12Y 301/08Phosphoric triester hydrolases49
- C12Y 301/11Exodeoxyribonucleases producing 5'-phosphomonoesters42
- C12Y 301/22Endodeoxyribonucleases producing 3'-phosphomonoesters30
- C12Y 301/30Endoribonucleases active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters16
- C12Y 301/07Diphosphoric monoester hydrolases14
- C12Y 301/31Endoribonucleases active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters14
- C12Y 301/13Exoribonucleases producing 5'-phosphomonoesters9
- C12Y 301/05Triphosphoric monoester hydrolases8
- C12Y 301/25Site-specific endodeoxyribonucleases specific for altered bases7
- C12Y 301/16Exonucleases active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters5
- C12Y 301/15Exonucleases active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters3
- C12Y 301/14Exoribonucleases producing 3'-phosphomonoesters0
Recent patents
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- Novel glycan compounds for age-related macular degeneration8 Oct 2026US 2026/0306530 A1The Regents of the University of California
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Most cited
By later US patents
- Engineering of systems, methods and optimized guide compositions for sequence manipulation480US 8,906,616 B2Massachusetts Institute of Technology · 2014
- Three-dimensional polymer matrices268US 6,471,993 B1Massachusetts Institute of Technology · 2002
- Modulated release from biocompatible polymers263US 5,656,297 AAlkermes Controlled Therapeutics, Inc. · 1997
- RNA-guided human genome engineering263US 9,023,649 B2President and Fellows of Harvard College · 2015
- Formulation of a reconstituted protein, and method and kit for the production thereof234US 5,580,856 A1996