C12P 35/00
Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system
Official title: Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin
C12P35/00 (Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system) appears on 223 US grants and 95 published applications in this corpus.
Search patents in C12P- Granted patents
- 223
- Published applications
- 95
- Assignees
- 98
- Inventors
- 591
- Latest grant
- 18 Nov 2025
Filings by year
| Year | Granted patents | Published applications |
|---|---|---|
| 1976 | 13 | 0 |
| 1977 | 7 | 0 |
| 1978 | 5 | 0 |
| 1979 | 6 | 0 |
| 1980 | 2 | 0 |
| 1981 | 7 | 0 |
| 1982 | 3 | 0 |
| 1983 | 5 | 0 |
| 1984 | 3 | 0 |
| 1985 | 7 | 0 |
| 1986 | 2 | 0 |
| 1987 | 3 | 0 |
| 1988 | 4 | 0 |
| 1989 | 1 | 0 |
| 1990 | 2 | 0 |
| 1991 | 2 | 0 |
| 1992 | 3 | 0 |
| 1993 | 3 | 0 |
| 1994 | 12 | 0 |
| 1995 | 10 | 0 |
| 1996 | 6 | 0 |
| 1997 | 9 | 0 |
| 1998 | 11 | 0 |
| 1999 | 9 | 0 |
| 2000 | 10 | 0 |
| 2001 | 6 | 1 |
| 2002 | 10 | 7 |
| 2003 | 5 | 10 |
| 2004 | 4 | 8 |
| 2005 | 4 | 3 |
| 2006 | 1 | 8 |
| 2007 | 4 | 3 |
| 2008 | 2 | 3 |
| 2009 | 4 | 5 |
| 2010 | 1 | 3 |
| 2011 | 5 | 4 |
| 2012 | 0 | 1 |
| 2013 | 3 | 3 |
| 2014 | 3 | 5 |
| 2015 | 3 | 8 |
| 2016 | 3 | 3 |
| 2017 | 1 | 3 |
| 2018 | 7 | 3 |
| 2019 | 0 | 6 |
| 2020 | 3 | 2 |
| 2021 | 3 | 1 |
| 2022 | 3 | 0 |
| 2023 | 1 | 1 |
| 2024 | 1 | 2 |
| 2025 | 1 | 0 |
| 2026 | 0 | 2 |
By publication year. Applications have been published since 2001. 2026 runs to 8 Oct.
Subgroups
Granted patents
Recent patents
- One-step method for synthesizing amoxicillin from penicillin or salt thereof through enzyme catalysis18 Nov 2025US 12,473,580 B1Xingzhi College Zhejiang Normal University
- Polypeptide having cephalosporin C acylase activity and use thereof2 Jul 2024US 12,024,729 B2Amicogen, Inc.
- Xylose isomerases that confer efficient xylose fermentation capability to yeast4 Jul 2023US 11,692,187 B2GlobalYeast N.V.
- Compositions and methods for the production of compounds20 Sep 2022US 11,447,810 B2Ginkgo Bioworks, Inc.
- Process for enzymatic hydrolysis of lignocellulosic material and fermentation of sugars6 Sep 2022US 11,434,507 B2Dsm IP Assets B.V.
- Biosynthesis of beta-lactam antibiotics24 Sep 2026US 2026/0286334 A1
- Mutant penicillin acylase and uses thereof30 Apr 2026US 2026/0117216 A1Xingzhi College Zhejiang Normal University
- Deacetoxycephalosporin c-producing microorganism for 7-adca production with high concentration and high purity and production method using the same16 May 2024US 2024/0158822 A1Amicogen, Inc.
- Protein-based material for biocatalysis11 Apr 2024US 2024/0116992 A1Bondwell Technologies LP
- Polypeptide having cephalosporin c acylase activity and use thereof24 Aug 2023US 2023/0265409 A1Amicogen, Inc.
Most cited
By later US patents
- Fluorogenic substrates for .beta.-lactamase and methods of use85US 5,741,657 AThe Regents of the University of California · 1998
- Cephalosporin acetylhydrolase gene and protein encoded by said gene77US 5,338,676 AShionogi & Co., Ltd. · 1994
- Transformed eukaryotic cells that directly convert xylose to xylulose63US 7,622,284 B2Royal Nedalco B.V. · 2009
- Cephalosporin acetylhydrolase gene from Bacillus subtilis46US 5,281,525 AShionogi & Co., Ltd. · 1994
- Nucleic acid molecule encoding a cephalosporin acetylesterase43US 6,465,233 B1Biochemie Gesellschaft m.b.H. · 2002