C12N 9/6429
Thrombin
Official title: {Thrombin (3.4.21.5)}
C12N9/6429 (Thrombin) appears on 213 US grants and 179 published applications in this corpus.
Search patents in C12N- Granted patents
- 213
- Published applications
- 179
- Assignees
- 158
- Inventors
- 520
- Latest grant
- 14 Jul 2026
Filings by year
| Year | Granted patents | Published applications |
|---|---|---|
| 1977 | 1 | 0 |
| 1978 | 1 | 0 |
| 1979 | 1 | 0 |
| 1980 | 1 | 0 |
| 1981 | 5 | 0 |
| 1982 | 2 | 0 |
| 1983 | 3 | 0 |
| 1984 | 2 | 0 |
| 1985 | 1 | 0 |
| 1986 | 1 | 0 |
| 1987 | 4 | 0 |
| 1988 | 1 | 0 |
| 1989 | 0 | 0 |
| 1990 | 4 | 0 |
| 1991 | 1 | 0 |
| 1992 | 4 | 0 |
| 1993 | 3 | 0 |
| 1994 | 3 | 0 |
| 1995 | 6 | 0 |
| 1996 | 6 | 0 |
| 1997 | 6 | 0 |
| 1998 | 14 | 0 |
| 1999 | 8 | 0 |
| 2000 | 13 | 0 |
| 2001 | 9 | 0 |
| 2002 | 3 | 7 |
| 2003 | 6 | 6 |
| 2004 | 4 | 9 |
| 2005 | 2 | 7 |
| 2006 | 4 | 10 |
| 2007 | 3 | 4 |
| 2008 | 4 | 8 |
| 2009 | 1 | 6 |
| 2010 | 6 | 7 |
| 2011 | 8 | 5 |
| 2012 | 5 | 5 |
| 2013 | 1 | 8 |
| 2014 | 4 | 9 |
| 2015 | 7 | 3 |
| 2016 | 6 | 13 |
| 2017 | 3 | 7 |
| 2018 | 6 | 7 |
| 2019 | 5 | 12 |
| 2020 | 4 | 9 |
| 2021 | 9 | 9 |
| 2022 | 5 | 10 |
| 2023 | 5 | 6 |
| 2024 | 6 | 6 |
| 2025 | 3 | 4 |
| 2026 | 3 | 2 |
By publication year. Applications have been published since 2001. 2026 runs to 8 Oct.
Recent patents
- Gla domains as therapeutic agents14 Jul 2026US 12,678,481 B2Gladiator Biosciences, Inc.
- Method for extracting unfractionated heparin from camel intestinal mucosa3 Mar 2026US 12,565,541 B1Camelx Biomedical & Research
- Gla domains as targeting agents20 Jan 2026US 12,527,836 B2Gladiator Biosciences, Inc.
- Method for purifying and quantifying thrombin and its degradation polypeptides8 Jul 2025US 12,351,843 B2Omrix Biopharmaceuticals Ltd.
- Targeting anabolic drugs for accelerated fracture repair3 Jun 2025US 12,319,721 B2Purdue Research Foundation
- Drug that promotes hemostasis8 Jan 2026US 2026/0007727 A1Biomedizinische Forschung & Bio-Produkte AG
- Targeting anabolic drugs for accelerated fracture repair8 Jan 2026US 2026/0008829 A1Purdue Research Foundation
- Peptides with multivalent effects9 Oct 2025US 2025/0313820 A1In2Cure AB
- Method of producing biologically active vitamin k dependent proteins by recombinant methods21 Aug 2025US 2025/0263769 A1Aptevo Biotherapeutics LLC
- Biosynthetic hemostat and uses thereof1 May 2025US 2025/0134969 A1Case Western Reserve University
Most cited
By later US patents
- Hemostatic agent270US 4,655,211 AUnitika Ltd. · 1987
- Aptamers specific for biomolecules and methods of making191US 5,756,291 AGilead Sciences, Inc. · 1998
- Method for preparing thrombin for use in a biological glue187US 6,472,162 B1ThermoGenesis Corp. · 2002
- Oil-body proteins as carriers of high-value peptides in plants136US 5,650,554 ASemBioSys Genetics Inc. · 1997
- Composition containing autologous thrombin blood fraction for use in a medical procedure136US 5,795,571 ABristol-Myers Squibb Company · 1998