C12N 15/115
Aptamers, i.e. nucleic acids binding a target molecule specifically and with high
Official title: Aptamers, i.e. nucleic acids binding a target molecule specifically and with high affinity without hybridising therewith {; Nucleic acids binding to non-nucleic acids, e.g. aptamers}
C12N15/115 (Aptamers, i.e. nucleic acids binding a target molecule specifically and with high) appears on 1,538 US grants and 2,593 published applications in this corpus.
Search patents in C12N- Granted patents
- 1,538
- Published applications
- 2,593
- Assignees
- 881
- Inventors
- 3,635
- Latest grant
- 29 Sep 2026
Filings by year
| Year | Granted patents | Published applications |
|---|---|---|
| 1995 | 4 | 0 |
| 1996 | 9 | 0 |
| 1997 | 24 | 0 |
| 1998 | 34 | 0 |
| 1999 | 17 | 0 |
| 2000 | 15 | 0 |
| 2001 | 14 | 0 |
| 2002 | 12 | 8 |
| 2003 | 6 | 31 |
| 2004 | 5 | 31 |
| 2005 | 7 | 77 |
| 2006 | 4 | 44 |
| 2007 | 6 | 30 |
| 2008 | 11 | 27 |
| 2009 | 14 | 69 |
| 2010 | 20 | 45 |
| 2011 | 31 | 64 |
| 2012 | 23 | 78 |
| 2013 | 35 | 69 |
| 2014 | 40 | 81 |
| 2015 | 60 | 115 |
| 2016 | 73 | 132 |
| 2017 | 77 | 159 |
| 2018 | 108 | 159 |
| 2019 | 158 | 215 |
| 2020 | 150 | 202 |
| 2021 | 121 | 194 |
| 2022 | 113 | 224 |
| 2023 | 94 | 178 |
| 2024 | 90 | 144 |
| 2025 | 96 | 134 |
| 2026 | 67 | 83 |
By publication year. Applications have been published since 2001. 2026 runs to 8 Oct.
Recent patents
- Riboswitch modulated gene therapy for retinal diseases29 Sep 2026US 12,747,441 B2The Medical College of Wisconsin, Inc.
- Compounds and methods for reducing PLN expression22 Sep 2026US 12,742,170 B2Ionis Pharmaceuticals, Inc.
- Electrochemical detection nanostructure, systems and uses thereof15 Sep 2026US 12,735,712 B2Auburn University
- Method for detecting virus using SSDNA functionalized sensor15 Sep 2026US 12,736,531 B2University of Central Florida Research Foundation, Inc.
- RNA molecules, methods of producing circular RNA, and treatment methods15 Sep 2026US 12,737,877 B2Cornell University
- Modular platform for molecular conjugation8 Oct 2026US 2026/0306645 A1CamBrixBio Ltd
- Materials and methods for aptamer selection8 Oct 2026US 2026/0308599 A1The Penn State Research Foundation
- Dna aptamer capable of selectively binding to soluble flt-1 and carrier having said dna aptamer immobilized thereto8 Oct 2026US 2026/0308600 A1Tagcyx Biotechnologies
- Oligonucleotide compositions and methods thereof1 Oct 2026US 2026/0297573 A1Wave Life Sciences Ltd.
- Multiple measurements using an electrochemical aptamer-based sensor1 Oct 2026US 2026/0297592 A1The University of Melbourne
Most cited
By later US patents
- Nucleic acid ligands561US 5,475,096 AUniversity Research Corporation · 1995
- Systematic evolution of ligands by exponential enrichment: Solution SELEX337US 5,567,588 AUniversity Research Corporation · 1996
- Systematic evolution of ligands by exponential enrichment: chimeric selex281US 5,637,459 ANeXstar Pharmaceuticals, Inc. · 1997
- High-affinity nucleic acid ligands that discriminate between theophylline and caffeine277US 5,580,737 ANeXstar Pharmaceuticals, Inc. · 1996
- Systematic evolution of ligands by exponential enrichment: blended SELEX233US 5,683,867 ANeXstar Pharmaceuticals, Inc. · 1997