C12N 15/1034
Isolating an individual clone by screening libraries
Official title: {Isolating an individual clone by screening libraries}
C12N15/1034 (Isolating an individual clone by screening libraries) appears on 5,572 US grants and 9,754 published applications in this corpus.
Search patents in C12N- Granted patents
- 5,572
- Published applications
- 9,754
- Assignees
- 2,682
- Inventors
- 14,636
- Latest grant
- 6 Oct 2026
Filings by year
| Year | Granted patents | Published applications |
|---|---|---|
| 1981 | 1 | 0 |
| 1982 | 0 | 0 |
| 1983 | 0 | 0 |
| 1984 | 0 | 0 |
| 1985 | 1 | 0 |
| 1986 | 0 | 0 |
| 1987 | 1 | 0 |
| 1988 | 1 | 0 |
| 1989 | 0 | 0 |
| 1990 | 1 | 0 |
| 1991 | 0 | 0 |
| 1992 | 2 | 0 |
| 1993 | 8 | 0 |
| 1994 | 12 | 0 |
| 1995 | 17 | 0 |
| 1996 | 38 | 0 |
| 1997 | 66 | 0 |
| 1998 | 120 | 0 |
| 1999 | 92 | 0 |
| 2000 | 104 | 0 |
| 2001 | 140 | 42 |
| 2002 | 159 | 276 |
| 2003 | 127 | 429 |
| 2004 | 113 | 274 |
| 2005 | 86 | 279 |
| 2006 | 113 | 242 |
| 2007 | 88 | 214 |
| 2008 | 82 | 201 |
| 2009 | 76 | 252 |
| 2010 | 130 | 252 |
| 2011 | 122 | 246 |
| 2012 | 110 | 235 |
| 2013 | 146 | 297 |
| 2014 | 207 | 338 |
| 2015 | 185 | 342 |
| 2016 | 206 | 372 |
| 2017 | 241 | 377 |
| 2018 | 253 | 485 |
| 2019 | 287 | 508 |
| 2020 | 332 | 578 |
| 2021 | 354 | 620 |
| 2022 | 323 | 657 |
| 2023 | 330 | 683 |
| 2024 | 320 | 602 |
| 2025 | 334 | 555 |
| 2026 | 244 | 398 |
By publication year. Applications have been published since 2001. 2026 runs to 8 Oct.
Subgroups
Granted patents
- C12N 15/1037Screening libraries presented on the surface of microorganisms1,166
- C12N 15/1093General methods of preparing gene libraries, not provided for in other subgroups948
- C12N 15/1065Preparation or screening of tagged libraries933
- C12N 15/1058Directional evolution of libraries485
- C12N 15/1086Preparation or screening of expression libraries380
- C12N 15/1048Selex377
- C12N 15/1082Preparation or screening gene libraries by chromosomal integration of polynucleotide sequences, hr-357
- C12N 15/1075By coupling phenotype to genotype, not provided for in other groups of346
All 17 subgroupsShow fewer
- C12N 15/1068Template mediated chemical library synthesis344
- C12N 15/1055Protein x protein interaction300
- C12N 15/1079Screening libraries by altering the phenotype or phenotypic trait of the host230
- C12N 15/1062Mrna-display210
- C12N 15/1072Differential gene expression library synthesis184
- C12N 15/1089Design, preparation, screening or analysis of libraries using computer algorithms171
- C12N 15/1044Preparation or screening of libraries displayed on scaffold proteins125
- C12N 15/1051Gene trapping119
- C12N 15/1041Ribosome/polysome display75
Recent patents
- Peptide libraries with non-canonical amino acids6 Oct 2026US 12,753,205 B2Regeneron Pharmaceuticals, Inc.
- Orthogonal ubiquitin transfer as a method to identify cellular substrates of E3 ubiquitin ligases6 Oct 2026US 12,753,402 B2Georgia State University Research Foundation, Inc.
- Method for transducing protein-protein interactions6 Oct 2026US 12,753,403 B2ETH Zurich
- Method and use for construction of sequencing library based on DNA samples6 Oct 2026US 12,753,404 B2MGI Tech Co., Ltd.
- Methods for preparing a library of polynucleotide molecules6 Oct 2026US 12,753,405 B2Ultima Genomics, Inc.
- Polymerase variants8 Oct 2026US 2026/0308540 A1Twist Bioscience Corporation
- System, Kit, and Method for Continuous Directed Evolution8 Oct 2026US 2026/0308569 A1The Board of Trustees of the University of Illinois
- Rna probing and amplification methods for single cell analysis on fixed cells8 Oct 2026US 2026/0308570 A1Becton, Dickinson and Company
- Contiguity Preserving Transposition8 Oct 2026US 2026/0308571 A1Illumina Cambridge Limited
- Analysis of cellular samples8 Oct 2026US 2026/0308572 A110x Genomics, Inc.
Most cited
By later US patents
- Directed evolution of novel binding proteins2,450US 5,223,409 AProtein Engineering Corporation · 1993
- Production of chimeric antibodies - a combinatorial approach1,367US 5,565,332 ACambridge Antibody Technology Limited · 1996
- CRISPR-Cas systems and methods for altering expression of gene products1,186US 8,697,359 B1Massachusetts Institute of Technology · 2014
- Viruses expressing chimeric binding proteins1,136US 5,403,484 AProtein Engineering Corporation · 1995
- Directed evolution of novel binding proteins1,057US 5,571,698 AProtein Engineering Corporation · 1996