C12N 15/1055
Protein x protein interaction
Official title: {Protein x Protein interaction, e.g. two hybrid selection}
C12N15/1055 (Protein x protein interaction) appears on 300 US grants and 525 published applications in this corpus.
Search patents in C12N- Granted patents
- 300
- Published applications
- 525
- Assignees
- 282
- Inventors
- 1,081
- Latest grant
- 6 Oct 2026
Filings by year
| Year | Granted patents | Published applications |
|---|---|---|
| 1994 | 2 | 0 |
| 1995 | 1 | 0 |
| 1996 | 3 | 0 |
| 1997 | 4 | 0 |
| 1998 | 7 | 0 |
| 1999 | 11 | 0 |
| 2000 | 9 | 0 |
| 2001 | 15 | 5 |
| 2002 | 11 | 49 |
| 2003 | 13 | 41 |
| 2004 | 10 | 27 |
| 2005 | 16 | 29 |
| 2006 | 9 | 13 |
| 2007 | 11 | 16 |
| 2008 | 8 | 13 |
| 2009 | 9 | 21 |
| 2010 | 12 | 22 |
| 2011 | 10 | 12 |
| 2012 | 7 | 5 |
| 2013 | 6 | 12 |
| 2014 | 4 | 14 |
| 2015 | 6 | 14 |
| 2016 | 6 | 8 |
| 2017 | 8 | 16 |
| 2018 | 11 | 15 |
| 2019 | 7 | 14 |
| 2020 | 17 | 20 |
| 2021 | 9 | 17 |
| 2022 | 9 | 18 |
| 2023 | 14 | 46 |
| 2024 | 12 | 39 |
| 2025 | 12 | 22 |
| 2026 | 11 | 17 |
By publication year. Applications have been published since 2001. 2026 runs to 8 Oct.
Recent patents
- Orthogonal ubiquitin transfer as a method to identify cellular substrates of E3 ubiquitin ligases6 Oct 2026US 12,753,402 B2Georgia State University Research Foundation, Inc.
- Method for transducing protein-protein interactions6 Oct 2026US 12,753,403 B2ETH Zurich
- Discovery and evolution of biologically active metabolites8 Sep 2026US 12,729,458 B2The Regents of the University of Colorado, a body corporate
- Cell-based reporter assay for screening inhibitors of coronavirus RNA-dependent RNA polymerase activity7 Jul 2026US 12,674,148 B2Korea Institute of Oriental Medicine
- Cellular phenotype screening method2 Jun 2026US 12,644,203 B2Riken
- Antibodies that bind to c-type lectin domain family 2 member d (clec2d)17 Sep 2026US 2026/0274965 A1Zumutor Biologics Inc.
- Large-scale induction of protein-protein interactions to discover novel effector proteins for proximity-based therapeutics10 Sep 2026US 2026/0265728 A1The Children’s Hospital of Philadelphia
- Reagents and systems for generating biosensors3 Sep 2026US 2026/0258397 A1The Regents of the University of California
- Library of proximity probes and method of use27 Aug 2026US 2026/0250661 A1Olink Proteomics AB
- Methods of selecting binding reagents30 Jul 2026US 2026/0218166 A1Nautilus Subsidiary, Inc.
Most cited
By later US patents
- System to detect protein-protein interactions444US 5,283,173 AThe Research Foundation of State University of New York · 1994
- Interaction trap assay, reagents and uses thereof325US 6,200,759 B1President and Fellows of Harvard College · 2001
- Functional genomics using zinc finger proteins321US 6,599,692 B1Sangamo BioScience, Inc. · 2003
- Intraction trap assay, reagents and uses thereof320US 5,925,523 APresident and Fellows of Harvard College · 1999
- System to detect protein-protein interactions145US 5,468,614 AThe Research Foundation of State University of New York · 1995