Antibodies that bind to c-type lectin domain family 2 member d (clec2d)

An isolated anti-CLEC2D antibody or antigen-binding fragment thereof comprising a heavy chain variable domain (VH) and a light chain variable domain (VL),

• wherein the antibody or antigen-binding fragment thereof comprises:
• a) a VH comprising complementarity determining regions (CDR) CDR1, CDR2, and CDR3 of SEQ ID NOs:
• 433, 486, and 547, respectively, and a VL comprising CDR1, CDR2, and CDR3 of SEQ ID NOs:
• 654, 727, and 784, respectively;
• b) a VH comprising CDR1, CDR2, and CDR3 of SEQ ID NOs:
• 439, 492, and 590, respectively, and a VL comprising CDR1, CDR2, and CDR3 of SEQ ID NOs:
• 688, 755, and 828, respectively;
• c) a VH comprising CDR1, CDR2, and CDR3 of SEQ ID NOs:
• 439, 492, and 589, respectively, and a VL comprising CDR1, CDR2, and CDR3 of SEQ ID NOs:
• 687, 729, and 827, respectively;
• d) a VH comprising CDR1, CDR2, and CDR3 of SEQ ID NOs:
• 466, 521, and 603, respectively, and a VL comprising CDR1, CDR2, and CDR3 of SEQ ID NOs:
• 662, 732, and 814, respectively;
• or
• e) a VH comprising CDR1, CDR2, and CDR3 of SEQ ID NOs:
• 439, 492, and 553, respectively, and a VL comprising CDR1, CDR2, and CDR3 of SEQ ID NOs:
• 660, 733, and 790, respectively.