C12M 21/08
Bioreactors or fermenters specially adapted for specific uses: for producing artificial tissue
Official title: {for producing artificial tissue or for ex-vivo cultivation of tissue (prostheses A61F2/00, grafts A61L27/00)}
C12M21/08 (Bioreactors or fermenters specially adapted for specific uses: for producing artificial tissue) appears on 943 US grants and 1,675 published applications in this corpus.
Search patents in C12M- Granted patents
- 943
- Published applications
- 1,675
- Assignees
- 781
- Inventors
- 3,599
- Latest grant
- 6 Oct 2026
Filings by year
| Year | Granted patents | Published applications |
|---|---|---|
| 1976 | 1 | 0 |
| 1977 | 0 | 0 |
| 1978 | 0 | 0 |
| 1979 | 0 | 0 |
| 1980 | 0 | 0 |
| 1981 | 0 | 0 |
| 1982 | 0 | 0 |
| 1983 | 0 | 0 |
| 1984 | 1 | 0 |
| 1985 | 0 | 0 |
| 1986 | 0 | 0 |
| 1987 | 1 | 0 |
| 1988 | 1 | 0 |
| 1989 | 1 | 0 |
| 1990 | 0 | 0 |
| 1991 | 0 | 0 |
| 1992 | 0 | 0 |
| 1993 | 0 | 0 |
| 1994 | 0 | 0 |
| 1995 | 3 | 0 |
| 1996 | 3 | 0 |
| 1997 | 9 | 0 |
| 1998 | 10 | 0 |
| 1999 | 10 | 0 |
| 2000 | 7 | 0 |
| 2001 | 8 | 7 |
| 2002 | 6 | 10 |
| 2003 | 9 | 10 |
| 2004 | 3 | 11 |
| 2005 | 6 | 17 |
| 2006 | 4 | 15 |
| 2007 | 2 | 15 |
| 2008 | 6 | 17 |
| 2009 | 6 | 19 |
| 2010 | 13 | 28 |
| 2011 | 5 | 29 |
| 2012 | 9 | 28 |
| 2013 | 15 | 39 |
| 2014 | 25 | 54 |
| 2015 | 31 | 55 |
| 2016 | 29 | 84 |
| 2017 | 40 | 97 |
| 2018 | 48 | 97 |
| 2019 | 54 | 114 |
| 2020 | 60 | 129 |
| 2021 | 78 | 136 |
| 2022 | 75 | 130 |
| 2023 | 95 | 157 |
| 2024 | 105 | 159 |
| 2025 | 95 | 115 |
| 2026 | 69 | 103 |
By publication year. Applications have been published since 2001. 2026 runs to 8 Oct.
Recent patents
- Cell culture method and cell culture device used with cell culture method6 Oct 2026US 12,753,395 B2Yamaguchi University
- On-demand assembleable heterogeneous cell-culture platform29 Sep 2026US 12,747,420 B1North Carolina Agricultural and Technical State University
- Complex microfluidic models for ALS including NF biomarkers for ALS research and drug development29 Sep 2026US 12,748,102 B2Cedars-Sinai Medical Center
- Systems, devices and methods for engineered tissue construct transport and containment22 Sep 2026US 12,742,144 B2Humacyte Global, Inc.
- Bile duct chip and use thereof15 Sep 2026US 12,735,663 B2Kyoto University
- Microphysiological system devices with self-contained photonic integrated circuit sensors8 Oct 2026US 2026/0308497 A1University of Rochester
- Lymphoid tissues with switchable protein gradients8 Oct 2026US 2026/0308498 A1Georgia Tech Research Corporation
- Method for 3d printing of vascularized tissues and organs8 Oct 2026US 2026/0308499 A1Technische UniversitäT Berlin
- Bio-engineered human prostate gland and disease model1 Oct 2026US 2026/0297481 A1Arizona Board of Regents on Behalf of the University of Arizona
- Microbe-gut-joint axis multi-organ chip and preparation method thereof1 Oct 2026US 2026/0297482 A1Center for Neuromusculoskeletal Restorative Medicine Limited
Most cited
By later US patents
- Architecture tool and methods of use328US 6,986,739 B2Sciperio, Inc · 2006
- Vascularized perfused microtissue/micro-organ arrays324US 6,197,575 B1Massachusetts Institute of Technology · 2001
- Architecture tool and methods of use210US 7,857,756 B2Sciperio, Inc · 2010
- Application of shear flow stress to chondrocytes or chondrocyte stem cells to produce cartilage173US 5,928,945 AAdvanced Tissue Sciences, Inc. · 1999
- Automated, multicompartmental cell culture system158US 5,612,188 ACornell Research Foundation, Inc. · 1997