C07K 14/52
Cytokines
Official title: Cytokines; Lymphokines; Interferons
C07K14/52 (Cytokines) appears on 7,200 US grants and 9,927 published applications in this corpus.
Search patents in C07K- Granted patents
- 7,200
- Published applications
- 9,927
- Assignees
- 3,054
- Inventors
- 15,486
- Latest grant
- 6 Oct 2026
Filings by year
| Year | Granted patents | Published applications |
|---|---|---|
| 1976 | 5 | 0 |
| 1977 | 6 | 0 |
| 1978 | 1 | 0 |
| 1979 | 5 | 0 |
| 1980 | 6 | 0 |
| 1981 | 17 | 0 |
| 1982 | 12 | 0 |
| 1983 | 15 | 0 |
| 1984 | 30 | 0 |
| 1985 | 27 | 0 |
| 1986 | 21 | 0 |
| 1987 | 51 | 0 |
| 1988 | 59 | 0 |
| 1989 | 65 | 0 |
| 1990 | 61 | 0 |
| 1991 | 78 | 0 |
| 1992 | 80 | 0 |
| 1993 | 78 | 0 |
| 1994 | 84 | 0 |
| 1995 | 95 | 0 |
| 1996 | 122 | 0 |
| 1997 | 194 | 0 |
| 1998 | 263 | 0 |
| 1999 | 243 | 0 |
| 2000 | 190 | 0 |
| 2001 | 187 | 39 |
| 2002 | 199 | 316 |
| 2003 | 179 | 674 |
| 2004 | 145 | 347 |
| 2005 | 128 | 342 |
| 2006 | 202 | 300 |
| 2007 | 256 | 395 |
| 2008 | 185 | 292 |
| 2009 | 225 | 300 |
| 2010 | 195 | 301 |
| 2011 | 174 | 294 |
| 2012 | 170 | 245 |
| 2013 | 178 | 275 |
| 2014 | 182 | 288 |
| 2015 | 175 | 243 |
| 2016 | 192 | 305 |
| 2017 | 169 | 282 |
| 2018 | 194 | 350 |
| 2019 | 195 | 422 |
| 2020 | 275 | 518 |
| 2021 | 298 | 547 |
| 2022 | 280 | 571 |
| 2023 | 242 | 645 |
| 2024 | 265 | 668 |
| 2025 | 322 | 544 |
| 2026 | 180 | 424 |
By publication year. Applications have been published since 2001. 2026 runs to 8 Oct.
Subgroups
Granted patents
Recent patents
- IL-10 muteins6 Oct 2026US 12,753,217 B2Universite De Lille
- Drug-specific pharmacokinetic assay for IL-15 superagonist6 Oct 2026US 12,754,189 B2NantCell, Inc.
- Fusion polypeptide and polypeptide dimer, and use thereof29 Sep 2026US 12,747,275 B2Nanjing Normal University
- Targeting of human interferon antagonists22 Sep 2026US 12,741,998 B2Centre Hospitalier Regional Universitaire De Montpellier
- Cytokine immunotherapy22 Sep 2026US 12,742,182 B2VLP Therapeutics, LLC
- Targeted Immune Cell Therapy Utilizing TRAIL and TNF Mediated Apoptosis8 Oct 2026US 2026/0306542 A1Northeastern University
- Recombinant expression vector for interferon-beta secretion and attenuated salmonella strain transformed by means of same8 Oct 2026US 2026/0306554 A1The Industry & Academic Cooperation in Chungnam National University (IAC)
- Recombinant expression vector for secreting interleukin-12, and attenuated salmonella strain transformed therewith8 Oct 2026US 2026/0306555 A1The Industry & Academic Cooperation in Chungnam National University (IAC)
- A cytokine-like propeptide gene therapy platform8 Oct 2026US 2026/0308217 A1
- Fusion proteins of il-24 and immunostimulatory cytokines, nk cells expressing il-24 or fusion proteins, and methods of use thereof8 Oct 2026US 2026/0308218 A1Virginia Commonwealth University
Most cited
By later US patents
- Interleukin-1α antibodies1,029US 8,034,337 B2Xbiotech, Inc. · 2011
- Methods for in vitro recombination882US 5,605,793 AAffymax Technologies N.V. · 1997
- Methods and compositions for cellular and metabolic engineering844US 5,837,458 AMaxygen, Inc. · 1998
- DNA mutagenesis by random fragmentation and reassembly791US 5,830,721 AAffymax Technologies N.V. · 1998
- Gene therapy759US 5,399,346 AThe United States of America as represented by the Department of Health and Human Services · 1995