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US 8,034,337 B2Granted
Interleukin-1α antibodies
AssigneeXbiotech, Inc.
InventorJohn Simard
Life of this patent
Estimating the term…
Abstract
Fully human monoclonal Abs includes (i) an antigen-binding variable region that exhibits very high binding affinity for IL-1α and (ii) a constant region that is effective at both activating the complement system though C1q binding and binding to several different Fc receptors.
Claims1
A purified human IgG1 monoclonal antibody that specifically binds to human interleukin-1 alpha, the monoclonal antibody comprising a heavy chain covalently joined to a light chain, wherein the heavy chain comprises the amino acid sequence of SEQ ID NO:
- 9 and the light chain comprises the amino acid sequence of SEQ ID NO:11.
Dependencies are inferred from the claim text.