B01J 2219/00621
By physical means
Official title: by physical means, e.g. trenches, raised areas
B01J2219/00621 (By physical means) appears on 761 US grants and 961 published applications in this corpus.
Search patents in B01J- Granted patents
- 761
- Published applications
- 961
- Assignees
- 365
- Inventors
- 1,619
- Latest grant
- 11 Aug 2026
Filings by year
| Year | Granted patents | Published applications |
|---|---|---|
| 1986 | 1 | 0 |
| 1987 | 0 | 0 |
| 1988 | 1 | 0 |
| 1989 | 1 | 0 |
| 1990 | 1 | 0 |
| 1991 | 0 | 0 |
| 1992 | 3 | 0 |
| 1993 | 1 | 0 |
| 1994 | 4 | 0 |
| 1995 | 4 | 0 |
| 1996 | 8 | 0 |
| 1997 | 12 | 0 |
| 1998 | 23 | 0 |
| 1999 | 20 | 0 |
| 2000 | 30 | 0 |
| 2001 | 50 | 39 |
| 2002 | 57 | 119 |
| 2003 | 67 | 118 |
| 2004 | 52 | 101 |
| 2005 | 48 | 91 |
| 2006 | 34 | 50 |
| 2007 | 26 | 33 |
| 2008 | 39 | 56 |
| 2009 | 24 | 48 |
| 2010 | 30 | 26 |
| 2011 | 36 | 32 |
| 2012 | 15 | 23 |
| 2013 | 21 | 18 |
| 2014 | 23 | 13 |
| 2015 | 9 | 18 |
| 2016 | 19 | 23 |
| 2017 | 11 | 18 |
| 2018 | 5 | 23 |
| 2019 | 16 | 9 |
| 2020 | 11 | 13 |
| 2021 | 12 | 11 |
| 2022 | 11 | 18 |
| 2023 | 9 | 14 |
| 2024 | 6 | 24 |
| 2025 | 13 | 11 |
| 2026 | 8 | 12 |
By publication year. Applications have been published since 2001. 2026 runs to 8 Oct.
Recent patents
- Flow cells and methods for making the same11 Aug 2026US 12,702,976 B2Illumina, Inc.
- Methods for making flow cells16 Jun 2026US 12,654,165 B2Illumina, Inc.
- De novo synthesized gene libraries10 Mar 2026US 12,569,822 B2Twist Bioscience Corporation
- Hydrogel-free surface functionalization for sequencing10 Mar 2026US 12,570,831 B2Illumina, Inc.
- Sequencing chip and manufacturing method therefor27 Jan 2026US 12,538,721 B2Bgi Shenzhen
- Methods for making flow cell surfaces17 Sep 2026US 2026/0273495 A1Illumina, Inc.
- On-flow cell three dimensional polymer structures20 Aug 2026US 2026/0241381 A1Illumina, Inc.
- Biochip manufacturing method and product thereof, and testing method using biochip23 Jul 2026US 2026/0208186 A1
- Gene sequencing chip, packaging structure, system and method for cleaning and manufacturing thereof, and sequencing method using the same9 Jul 2026US 2026/0193704 A1MGI Tech Co., Ltd.
- Compositions, methods, and systems for sample processing with morphology-adjustable functionalized particles18 Jun 2026US 2026/0166542 A1Bio-Rad Laboratories, Inc.
Most cited
By later US patents
- Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof1,998US 5,143,854 AAffymax Technologies N.V. · 1992
- Array of oligonucleotides on a solid substrate1,585US 5,445,934 AAffymax Technologies N.V. · 1995
- Method and apparatus for conducting an array of chemical reactions on a support surface1,036US 5,474,796 AProtogene Laboratories, Inc. · 1995
- Method of sampling, amplifying and quantifying segment of nucleic acid, polymerase chain reaction assembly having nanoliter-sized sample chambers, and method of filling assembly971US 6,143,496 ACytonix Corporation · 2000
- Method of detecting nucleic acids962US 5,800,992 A1998