A61K 38/4873
Cysteine endopeptidases
Official title: {Cysteine endopeptidases (3.4.22), e.g. stem bromelain, papain, ficin, cathepsin H}
A61K38/4873 (Cysteine endopeptidases) appears on 257 US grants and 535 published applications in this corpus.
Search patents in A61K- Granted patents
- 257
- Published applications
- 535
- Assignees
- 239
- Inventors
- 759
- Latest grant
- 6 Oct 2026
Filings by year
| Year | Granted patents | Published applications |
|---|---|---|
| 1981 | 2 | 0 |
| 1982 | 1 | 0 |
| 1983 | 0 | 0 |
| 1984 | 3 | 0 |
| 1985 | 0 | 0 |
| 1986 | 1 | 0 |
| 1987 | 1 | 0 |
| 1988 | 0 | 0 |
| 1989 | 0 | 0 |
| 1990 | 0 | 0 |
| 1991 | 2 | 0 |
| 1992 | 2 | 0 |
| 1993 | 1 | 0 |
| 1994 | 1 | 0 |
| 1995 | 2 | 0 |
| 1996 | 5 | 0 |
| 1997 | 1 | 0 |
| 1998 | 3 | 0 |
| 1999 | 3 | 0 |
| 2000 | 2 | 0 |
| 2001 | 3 | 3 |
| 2002 | 5 | 12 |
| 2003 | 2 | 14 |
| 2004 | 6 | 20 |
| 2005 | 3 | 15 |
| 2006 | 5 | 17 |
| 2007 | 2 | 19 |
| 2008 | 3 | 23 |
| 2009 | 3 | 18 |
| 2010 | 5 | 20 |
| 2011 | 8 | 36 |
| 2012 | 11 | 20 |
| 2013 | 8 | 19 |
| 2014 | 12 | 24 |
| 2015 | 14 | 26 |
| 2016 | 21 | 20 |
| 2017 | 14 | 28 |
| 2018 | 22 | 22 |
| 2019 | 14 | 29 |
| 2020 | 10 | 13 |
| 2021 | 14 | 21 |
| 2022 | 11 | 21 |
| 2023 | 9 | 32 |
| 2024 | 9 | 26 |
| 2025 | 7 | 15 |
| 2026 | 6 | 22 |
By publication year. Applications have been published since 2001. 2026 runs to 8 Oct.
Recent patents
- Protease composition6 Oct 2026US 12,751,997 B2Anatara Lifesciences Limited
- Bromelain protease, bromelain, jacalin-like lectin, extract from the stem and/or the fruit of a pineapple plant, combination preparation, bromelain protease inhibitor, protein/protease mix, and glycated bromelain protein formed by exogenous non-enzymatic glycation, for use in the treatment or prophylaxis of virus infections caused by coronaviruses in a human or animal15 Sep 2026US 12,734,223 B2Helmholtz-Institut FüR Pharmazeutische Forschung Saarland
- Compositions comprising a tweak ligand and methods of using same25 Aug 2026US 12,714,740 B2Children's Hospital Medical Center
- Methods for treating Covid-1916 Jun 2026US 12,653,806 B2Medstar Health, Inc.
- Method for treating and/or improving inflammatory intestinal disease10 Mar 2026US 12,569,545 B2Tunghai University
- Methods for developing companion supplements for dogs, related compositions, and systems17 Sep 2026US 2026/0272876 A1Life's Abundance
- Gastrointestinal health supplements10 Sep 2026US 2026/0263548 A1Bimini LLC
- Co-treatment for gene therapy6 Aug 2026US 2026/0224671 A1Hansa Biopharma AB
- Enhancement and stabilisation of proteolytic activity of proteases6 Aug 2026US 2026/0226451 A1Phoenix Eagle Company Pty. Ltd.
- Implantable Device for Sustained Release of a Macromolecular Drug Compound23 Jul 2026US 2026/0207523 A1Celanese EVA Performance Polymers LLC
Most cited
By later US patents
- Enzyme-containing digestive aid compostions92US 4,447,412 A1984
- Engineered enzymes and uses thereof79US 7,335,504 B2DIREVO Biotechnology AG · 2008
- Oral composition providing enhanced tooth stain removal77US 6,379,654 B1Colgate-Palmolive Company · 2002
- Delivery of nucleotides into organisms by electroporation74US 5,749,847 AMassachusetts Institute of Technology · 1998
- Dietary supplement and method for use as a probiotic, for alleviating the symptons associated with irritable bowel syndrome71US 6,203,797 B12001