A61K 38/43
Enzymes
Official title: Enzymes; Proenzymes; Derivatives thereof
A61K38/43 (Enzymes) appears on 8,049 US grants and 15,011 published applications in this corpus.
Search patents in A61K- Granted patents
- 8,049
- Published applications
- 15,011
- Assignees
- 4,404
- Inventors
- 20,052
- Latest grant
- 6 Oct 2026
Filings by year
| Year | Granted patents | Published applications |
|---|---|---|
| 1976 | 7 | 0 |
| 1977 | 11 | 0 |
| 1978 | 4 | 0 |
| 1979 | 9 | 0 |
| 1980 | 6 | 0 |
| 1981 | 12 | 0 |
| 1982 | 7 | 0 |
| 1983 | 6 | 0 |
| 1984 | 16 | 0 |
| 1985 | 13 | 0 |
| 1986 | 11 | 0 |
| 1987 | 12 | 0 |
| 1988 | 12 | 0 |
| 1989 | 15 | 0 |
| 1990 | 28 | 0 |
| 1991 | 29 | 0 |
| 1992 | 39 | 0 |
| 1993 | 35 | 0 |
| 1994 | 40 | 0 |
| 1995 | 40 | 0 |
| 1996 | 55 | 0 |
| 1997 | 64 | 0 |
| 1998 | 93 | 0 |
| 1999 | 103 | 0 |
| 2000 | 98 | 0 |
| 2001 | 112 | 57 |
| 2002 | 137 | 260 |
| 2003 | 122 | 317 |
| 2004 | 90 | 360 |
| 2005 | 110 | 356 |
| 2006 | 119 | 393 |
| 2007 | 111 | 378 |
| 2008 | 125 | 428 |
| 2009 | 105 | 420 |
| 2010 | 179 | 482 |
| 2011 | 181 | 508 |
| 2012 | 250 | 479 |
| 2013 | 306 | 629 |
| 2014 | 373 | 711 |
| 2015 | 397 | 747 |
| 2016 | 428 | 814 |
| 2017 | 465 | 777 |
| 2018 | 451 | 745 |
| 2019 | 474 | 830 |
| 2020 | 483 | 810 |
| 2021 | 453 | 843 |
| 2022 | 421 | 863 |
| 2023 | 344 | 784 |
| 2024 | 415 | 771 |
| 2025 | 371 | 717 |
| 2026 | 262 | 532 |
By publication year. Applications have been published since 2001. 2026 runs to 8 Oct.
Subgroups
Granted patents
Recent patents
- Protease composition6 Oct 2026US 12,751,997 B2Anatara Lifesciences Limited
- Method for modulating RNA splicing by inducing base mutation at splice site or base substitution in polypyrimidine region6 Oct 2026US 12,753,420 B2Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences
- Methods and compositions for delivery of agents across the blood-brain barrier29 Sep 2026US 12,747,269 B2The Brigham and Women S Hospital, Inc.
- Engineered meganucleases having specificity for a recognition sequence in the transthyretin gene29 Sep 2026US 12,747,430 B2Precision BioSciences, Inc.
- Methods of treating ischemic disease by administering an ATR kinase inhibitor22 Sep 2026US 12,740,980 B2East Tennessee State University Research Foundation
- Cosmetic composition comprising an endolysin and an organic filler8 Oct 2026US 2026/0306385 A1L'oreal
- Perfluorocarbon compositions, systems, and methods for ischemic, inflammatory, infectuous, transplant, and other medical conditions8 Oct 2026US 2026/0306422 A1
- Novel glycan compounds for age-related macular degeneration8 Oct 2026US 2026/0306530 A1The Regents of the University of California
- Composition for inducing immunotolerance8 Oct 2026US 2026/0306540 A1
- Plasmin-induced internal limiting membrane digestion facilitates donor retinal ganglion cell transplantation8 Oct 2026US 2026/0306549 A1University of Pittsburgh—Of the Commonwealth System of Higher Education
Most cited
By later US patents
- Non-immunogenic polypeptides2,007US 4,179,337 A1979
- Device for priming for improved adherence of gels to substrates1,210US 5,749,968 AFocal, Inc. · 1998
- CRISPR-Cas systems and methods for altering expression of gene products1,186US 8,697,359 B1Massachusetts Institute of Technology · 2014
- Drug delivery system making use of a hydrogel polymer coating1,007US 5,304,121 ABoston Scientific Corporation · 1994
- Drug-delivering composite structures814US 9,446,226 B2Ramot at Tel-Aviv University Ltd. · 2016