A61K 38/53
Ligases
Official title: Ligases (6)
A61K38/53 (Ligases) appears on 130 US grants and 231 published applications in this corpus.
Search patents in A61K- Granted patents
- 130
- Published applications
- 231
- Assignees
- 105
- Inventors
- 299
- Latest grant
- 21 Jul 2026
Filings by year
| Year | Granted patents | Published applications |
|---|---|---|
| 1978 | 1 | 0 |
| 1979 | 0 | 0 |
| 1980 | 0 | 0 |
| 1981 | 0 | 0 |
| 1982 | 0 | 0 |
| 1983 | 0 | 0 |
| 1984 | 0 | 0 |
| 1985 | 0 | 0 |
| 1986 | 0 | 0 |
| 1987 | 0 | 0 |
| 1988 | 0 | 0 |
| 1989 | 0 | 0 |
| 1990 | 0 | 0 |
| 1991 | 0 | 0 |
| 1992 | 0 | 0 |
| 1993 | 0 | 0 |
| 1994 | 0 | 0 |
| 1995 | 1 | 0 |
| 1996 | 0 | 0 |
| 1997 | 1 | 0 |
| 1998 | 0 | 0 |
| 1999 | 1 | 0 |
| 2000 | 0 | 0 |
| 2001 | 1 | 1 |
| 2002 | 0 | 1 |
| 2003 | 1 | 2 |
| 2004 | 1 | 3 |
| 2005 | 0 | 3 |
| 2006 | 1 | 13 |
| 2007 | 1 | 3 |
| 2008 | 1 | 8 |
| 2009 | 0 | 4 |
| 2010 | 2 | 4 |
| 2011 | 1 | 6 |
| 2012 | 2 | 5 |
| 2013 | 4 | 25 |
| 2014 | 6 | 9 |
| 2015 | 19 | 20 |
| 2016 | 13 | 11 |
| 2017 | 16 | 25 |
| 2018 | 11 | 11 |
| 2019 | 10 | 12 |
| 2020 | 6 | 14 |
| 2021 | 6 | 6 |
| 2022 | 5 | 14 |
| 2023 | 4 | 6 |
| 2024 | 5 | 13 |
| 2025 | 5 | 4 |
| 2026 | 5 | 8 |
By publication year. Applications have been published since 2001. 2026 runs to 8 Oct.
Recent patents
- Polynucleotides encoding propionyl-CoA carboxylase alpha and beta subunits for the treatment of propionic acidemia21 Jul 2026US 12,685,785 B2ModernaTX, Inc.
- TARS derived from Akkermansia muciniphila or fragment thereof, and use thereof26 May 2026US 12,636,342 B2Korea Research Institute of Bioscience and Biotechnology
- Methods for improved therapeutic use of recombinant AAV10 Feb 2026US 12,544,437 B2Ultragenyx Pharmaceutical Inc.
- Compositions and uses thereof27 Jan 2026US 12,533,392 B2SkinBio Therapeutics PLC
- MRNA therapy for argininosuccinate synthetase deficiency27 Jan 2026US 12,533,402 B2Translate Bio, Inc.
- Combination therapy methods, compositions and kits13 Aug 2026US 2026/0232752 A1Accure Therapeutics, S.L.
- A novel marker for cardiomyocytes dedifferentiation13 Aug 2026US 2026/0235604 A1National University of Singapore
- Compositions and methods for providing effects6 Aug 2026US 2026/0224625 A1G Tech Bio LLC
- Compositions and uses thereof16 Jul 2026US 2026/0199428 A1Skinbiotherapeutics PLC
- Methods for improved therapeutic use of recombinant aav14 May 2026US 2026/0130990 A1Ultragenyx Pharmaceutical Inc.
Most cited
By later US patents
- Human aminoacyl-tRNA synthetase polypeptides useful for the regulation of angiogenesis96US 7,144,984 B2The Scripps Research Institute · 2006
- Anti-apoptotic use of human glutaminyl-tRNA synthetase with two consecutive pro-apoptotic mediators88US 6,548,060 B12003
- Use of AIM3 acting as a tumor suppressor88US 7,902,165 B2Seoul National University Industry Foundation · 2011
- Compositions and methods comprising glycyl-tRNA synthetases having non-canonical biological activities71US 8,404,471 B2aTyr Pharma, Inc. · 2013
- Lipid formulations for delivery of messenger RNA42US 9,629,804 B2Massachusetts Institute of Technology · 2017