A61K 31/381
Having five-membered rings
Official title: having five-membered rings
A61K31/381 (Having five-membered rings) appears on 1,749 US grants and 3,078 published applications in this corpus.
Search patents in A61K- Granted patents
- 1,749
- Published applications
- 3,078
- Assignees
- 1,318
- Inventors
- 6,895
- Latest grant
- 6 Oct 2026
Filings by year
| Year | Granted patents | Published applications |
|---|---|---|
| 1980 | 1 | 0 |
| 1981 | 0 | 0 |
| 1982 | 0 | 0 |
| 1983 | 0 | 0 |
| 1984 | 1 | 0 |
| 1985 | 0 | 0 |
| 1986 | 0 | 0 |
| 1987 | 0 | 0 |
| 1988 | 0 | 0 |
| 1989 | 0 | 0 |
| 1990 | 0 | 0 |
| 1991 | 1 | 0 |
| 1992 | 0 | 0 |
| 1993 | 0 | 0 |
| 1994 | 1 | 0 |
| 1995 | 6 | 0 |
| 1996 | 25 | 0 |
| 1997 | 16 | 0 |
| 1998 | 20 | 0 |
| 1999 | 23 | 0 |
| 2000 | 35 | 0 |
| 2001 | 38 | 7 |
| 2002 | 36 | 51 |
| 2003 | 31 | 98 |
| 2004 | 32 | 82 |
| 2005 | 27 | 77 |
| 2006 | 37 | 91 |
| 2007 | 21 | 100 |
| 2008 | 23 | 76 |
| 2009 | 29 | 98 |
| 2010 | 37 | 83 |
| 2011 | 33 | 107 |
| 2012 | 37 | 96 |
| 2013 | 74 | 132 |
| 2014 | 103 | 162 |
| 2015 | 87 | 191 |
| 2016 | 112 | 159 |
| 2017 | 110 | 172 |
| 2018 | 117 | 146 |
| 2019 | 86 | 133 |
| 2020 | 109 | 160 |
| 2021 | 90 | 166 |
| 2022 | 92 | 155 |
| 2023 | 64 | 118 |
| 2024 | 82 | 150 |
| 2025 | 70 | 158 |
| 2026 | 43 | 110 |
By publication year. Applications have been published since 2001. 2026 runs to 8 Oct.
Recent patents
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- Inhibitors of the peptidyl-prolyl cis/trans isomerase (PIN1), combinations and uses thereof8 Sep 2026US 12,728,132 B2Beth Israel Deaconess Medical Center, Inc.
- Arylsulfonamides as orexin receptor agonists8 Sep 2026US 12,729,178 B2Research Triangle Institute
- Inhaled statins as bronchodilators to improve lung function in respiratory diseases8 Oct 2026US 2026/0306477 A1Beth Israel Deaconess Medical Center, Inc.
- Inverse agonists of rar related orphan receptors (rors)8 Oct 2026US 2026/0306484 A111949098 CANADA INC. (NUREDCO) c/o Jean I. TCHERVENKOV
- Methods and pharmaceutical compositions comprising d1-like dopamine receptor agonist for the treatment of autosomal dominant polycystic kidney disease8 Oct 2026US 2026/0306504 A1Centre Hospitalier Universitaire De Rouen
- Uric acid transporter agonist compound, pharmaceutical composition, and preparation method therefor and use thereof8 Oct 2026US 2026/0308136 A1Hangzhou E & J Biopharmaceutical Technology Co., Ltd.
- Novel carboxamide derivatives8 Oct 2026US 2026/0308149 A1Angelini Pharma S.P.A.
Most cited
By later US patents
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- Compositions and methods for increasing the metabolic lifetime of dextromethorphan and related pharmacodynamic effects153US 9,700,528 B2Antecip Bioventures II LLC · 2017
- Compositions and methods for increasing the metabolic lifetime of dextromethorphan and related pharmacodynamic effects147US 9,457,023 B1Antecip Bioventures II LLC · 2016
- Compounds and therapies for the prevention of vascular and non-vascular pathologies146US 6,117,911 ANeoRx Corporation · 2000