C12Y 203/03013
2-isopropylmalate synthase
Official title: 2-Isopropylmalate synthase (2.3.3.13)
C12Y203/03013 (2-isopropylmalate synthase) appears on 26 US grants and 33 published applications in this corpus.
Search patents in C12Y- Granted patents
- 26
- Published applications
- 33
- Assignees
- 21
- Inventors
- 70
- Latest grant
- 21 Apr 2026
Filings by year
| Year | Granted patents | Published applications |
|---|---|---|
| 2009 | 0 | 1 |
| 2010 | 0 | 1 |
| 2011 | 0 | 1 |
| 2012 | 1 | 0 |
| 2013 | 1 | 0 |
| 2014 | 1 | 5 |
| 2015 | 2 | 4 |
| 2016 | 3 | 2 |
| 2017 | 2 | 1 |
| 2018 | 1 | 1 |
| 2019 | 1 | 2 |
| 2020 | 1 | 2 |
| 2021 | 2 | 2 |
| 2022 | 2 | 5 |
| 2023 | 0 | 1 |
| 2024 | 4 | 2 |
| 2025 | 2 | 2 |
| 2026 | 3 | 1 |
By publication year. 2026 runs to 8 Oct.
Recent patents
- Synthesis of beta-hydroxyisovalerate and methods of use21 Apr 2026US 12,606,850 B2Sasya Inc.
- Isopropylmalate synthase polypeptide variant and a method for producing L-leucine using the same17 Feb 2026US 12,553,069 B2Cj Cheiljedang Corporation
- Isopropylmalate synthase variant and a method of producing L-leucine using the same10 Feb 2026US 12,545,937 B2Cj Cheiljedang Corporation
- Method for producing 2-methyl-butyric acid by bacterial fermentation24 Jun 2025US 12,338,481 B2Ajinomoto Co., Inc.
- Synthesis of beta-hydroxyisovalerate and methods of use25 Feb 2025US 12,234,495 B2Sasya Inc.
- Isopropylmalate synthase polypeptide variant and a method for producing L-leucine using the same11 Jun 2026US 2026/0159862 A1Cj Cheiljedang Corporation
- Method for Regulating and Controlling Heterologous Synthetic Flavonoid Compound and Use Thereof20 Mar 2025US 2025/0092431 A1
- Synthesis of beta-hydroxyisovalerate and methods of use2 Jan 2025US 2025/0002949 A1Sasya Inc.
- Recombinant microorganism and l-leucine production method using same14 Nov 2024US 2024/0376483 A1Green Earth Institute Co., Ltd.
- Isopropylmalate synthase variant and a method of producing l-leucine using the same21 Mar 2024US 2024/0093252 A1Cj Cheiljedang Corporation
Most cited
By later US patents
- Increased production of isobutanol in yeast with reduced mitochondrial amino acid biosynthesis37US 8,465,964 B2Butamax (TM) Advanced Biofules LLC · 2013
- Increased production of isobutanol in yeast with reduced mitochondrial amino acid biosynthesis34US 8,785,166 B2Butamax Advanced Biofuels LLC · 2014
- Increased production of isobutanol in yeast with reduced mitochondrial amino acid biosynthesis9US 9,163,266 B2Butamax Advanced Biofuels LLC · 2015
- Increased production of isobutanol in yeast with reduced mitochondrial amino acid biosynthesis8US 9,404,117 B2Butamax Advanced Biofuels LLC · 2016
- Production of C5-C8 alcohols using evolved enzymes and metabolically engineered microorganisms7US 8,298,798 B2The Regents of the University of California · 2012