C12N 9/82
Asparaginase
Official title: Asparaginase {(3.5.1.1)}
C12N9/82 (Asparaginase) appears on 99 US grants and 136 published applications in this corpus.
Search patents in C12N- Granted patents
- 99
- Published applications
- 136
- Assignees
- 88
- Inventors
- 293
- Latest grant
- 31 Mar 2026
Filings by year
| Year | Granted patents | Published applications |
|---|---|---|
| 1978 | 1 | 0 |
| 1979 | 0 | 0 |
| 1980 | 0 | 0 |
| 1981 | 0 | 0 |
| 1982 | 0 | 0 |
| 1983 | 0 | 0 |
| 1984 | 1 | 0 |
| 1985 | 0 | 0 |
| 1986 | 0 | 0 |
| 1987 | 0 | 0 |
| 1988 | 1 | 0 |
| 1989 | 1 | 0 |
| 1990 | 0 | 0 |
| 1991 | 0 | 0 |
| 1992 | 0 | 0 |
| 1993 | 0 | 0 |
| 1994 | 1 | 0 |
| 1995 | 0 | 0 |
| 1996 | 0 | 0 |
| 1997 | 2 | 0 |
| 1998 | 4 | 0 |
| 1999 | 3 | 0 |
| 2000 | 5 | 0 |
| 2001 | 4 | 0 |
| 2002 | 2 | 4 |
| 2003 | 1 | 3 |
| 2004 | 0 | 1 |
| 2005 | 0 | 0 |
| 2006 | 2 | 3 |
| 2007 | 1 | 3 |
| 2008 | 1 | 3 |
| 2009 | 0 | 3 |
| 2010 | 3 | 7 |
| 2011 | 1 | 3 |
| 2012 | 4 | 11 |
| 2013 | 3 | 5 |
| 2014 | 1 | 4 |
| 2015 | 3 | 4 |
| 2016 | 5 | 18 |
| 2017 | 5 | 5 |
| 2018 | 7 | 10 |
| 2019 | 9 | 12 |
| 2020 | 7 | 8 |
| 2021 | 7 | 8 |
| 2022 | 3 | 8 |
| 2023 | 4 | 3 |
| 2024 | 2 | 3 |
| 2025 | 4 | 5 |
| 2026 | 1 | 2 |
By publication year. Applications have been published since 2001. 2026 runs to 8 Oct.
Recent patents
- Method for treating cancer31 Mar 2026US 12,590,966 B2Children's Medical Center Corporation
- Method of treating AML with PEGylated l-asparaginase14 Oct 2025US 12,441,992 B2Jazz Pharmaceuticals II SAS
- Asparaginase based selection system for heterologous protein expression in mammalian cells5 Aug 2025US 12,378,573 B2Technical University of Denmark
- Analyte sensors for detecting asparagine and aspartate and methods of use thereof1 Jul 2025US 12,345,671 B2Abbott Diabetes Care Inc.
- Immunotherapy with metabolic enzyme expression17 Jun 2025US 12,329,816 B2The Trustees of Princeton University
- Functionalized biocatalytical compositions9 Apr 2026US 2026/0097103 A1Perseo Pharma AG
- Combination therapies involving l-asparaginase8 Jan 2026US 2026/0007728 A1Jazz Pharmaceuticals Ireland Limited
- Novel tumor antigen-targeting anticancer agent11 Dec 2025US 2025/0376507 A1Industry Foundation of Chonnam National University
- Analyte sensors for detecting asparagine and aspartate and methods of use thereof13 Nov 2025US 2025/0347647 A1Abbott Diabetes Care Inc.
- Multimeric protein-albumin conjugate, preparation method therefor, and use thereof18 Sep 2025US 2025/0288686 A1Proabtech Inc.
Most cited
By later US patents
- Method of protein therapy by orally administering crosslinked protein crystals73US 6,011,001 AVertex Pharmaceuticals Incorporated · 2000
- PEGylated L-asparaginase39US 11,046,946 B2Jazz Pharmaceuticals II SAS · 2021
- Modified L-asparaginase38US 10,174,302 B1Jazz Pharmaceuticals Ireland Limited · 2019
- Crosslinked enzyme crystals38US 5,618,710 AVertex Pharmaceuticals Incorporated · 1997
- PEGylated L-asparaginase37US 9,920,311 B2Jazz Pharmaceuticals II SAS · 2018